1-Naphthalenol, 4-[(4-ethoxyphenyl)azo]- (CAS 6535-42-8) — Citrus N/A Note Fragrance Ingredient

Citrus · Floral

1-Naphthalenol, 4-[(4-ethoxyphenyl)azo]-

CAS 6535-42-8

Origin
synthetic
Note
N/A
IFRA
Professional use
Data as of: Apr 2026

What Is 1-Naphthalenol, 4-[(4-ethoxyphenyl)azo]-?

1-Naphthalenol, 4-[(4-ethoxyphenyl)azo]- is a synthetic azo dye used in industrial applications. While not commonly encountered in consumer products, it may appear in specialized materials. This compound matters because its structural properties make it useful in technical applications, though its safety profile requires careful handling.

Safety Profile

PROFESSIONAL USE
Generally safeUse with awarenessProfessional use
Handle with protective equipment
Not for consumer fragrance use
CAS
6535-42-8
Formula
Mixture
MW
Variable
Odor Family
Citrus · Floral
Layer 1 · Enthusiast

What Does 1-Naphthalenol, 4-[(4-ethoxyphenyl)azo]- Smell Like?

This synthetic compound lacks a distinctive olfactory profile suitable for perfumery. Its industrial nature prioritizes functional properties over aromatic qualities, making it unsuitable for traditional fragrance applications.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Layer 2

2D Molecular Structure

C.I. Solvent Red 3

SMILES: CCOC1=CC=C(C=C1)N=NC1=C2C=CC=CC2=C(O)C=C1

Chemistry, Properties & Perfumer Guide

The Chemistry

1-Naphthalenol, 4-[(4-ethoxyphenyl)azo]- is an azo compound characterized by its naphthalene backbone and ethoxyphenylazo functional group. Azo compounds are synthesized via diazotization followed by coupling reactions. This particular structure lacks significant fragrance utility due to its industrial focus and potential safety concerns.

Physical & Chemical Properties

Molecular WeightN/A
Boiling PointN/A

Perfumer Guide

Note Position
N/A
Volatility
N/A
Blending
N/A
ApplicationTypical %RangeNotes

Classic Accords

Tip: Not recommended for perfumery due to safety and lack of olfactory value.

Alternatives & Comparisons

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not listed in IFRA standards due to non-perfumery use.

GHS Classification

H315 Skin irritation H319 Eye irritation

RIFM Assessment

No RIFM assessment available for this compound.

Sustainability

This synthetic compound is produced for industrial purposes with no notable sustainable sourcing considerations.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Physicochemical Properties

    DTXSID: DTXSID6064402

    Physical Properties

    Molecular Weight 292.338 g/mol🔬 EPA CompTox
    Density 1.179 g/cm^3📊 OPERA
    Boiling Point 416.222 °C📊 OPERA
    Melting Point 159.984 °C📊 OPERA
    Flash Point 267.326 °C📊 OPERA
    Refractive Index 1.607 Dimensionless📊 OPERA
    Molar Volume 249.149 cm^3/mol📊 OPERA

    Partition & Solubility

    LogP (Octanol-Water) 4.326 Log10 unitless📊 OPERA
    LogD (pH 5.5) 4.326 Log10 unitless📊 OPERA
    LogD (pH 7.4) 4.315 Log10 unitless📊 OPERA
    LogKoa (Octanol-Air) 11.13 Log10 unitless📊 OPERA
    Water Solubility 0 mol/L📊 OPERA
    Henry's Law Constant 0 atm-m3/mole📊 OPERA

    Transport Properties

    Vapor Pressure 0 mmHg📊 OPERA
    Surface Tension 44.026 dyn/cm📊 OPERA

    Molecular Descriptors

    Topological Polar Surface Area 54.18 Ų💻 Computed
    H-Bond Donors 1 count💻 Computed
    H-Bond Acceptors 4 count💻 Computed
    Rotatable Bonds 4 count💻 Computed
    Aromatic Rings 3 count💻 Computed
    Molar Refractivity 86.018 cm^3/mol📊 OPERA
    Polarizability 34.1 Å^3📊 OPERA

    Data Sources:

    🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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