10-Dodecen-3-one, 5-hydroxy-7,11-dimethyl- (CAS 68922-12-3) — Floral Middle Note Fragrance Ingredient
10-Dodecen-3-one, 5-hydroxy-7,11-dimethyl-
CAS 68922-12-3
What Is 10-Dodecen-3-one, 5-hydroxy-7,11-dimethyl-?
10-Dodecen-3-one, 5-hydroxy-7,11-dimethyl- is a synthetic fragrance ingredient used in perfumery to create unique olfactory effects. It’s found in niche and artisanal fragrances. This molecule matters because it offers perfumers a tool to craft distinctive scent profiles that can’t be achieved with natural materials alone.
Safety Profile
USE WITH AWARENESSWhat Does 10-Dodecen-3-one, 5-hydroxy-7,11-dimethyl- Smell Like?
This synthetic ketone delivers a complex olfactory profile that evolves dramatically. The initial impression is sharp and metallic, like hot wires cooling, with a subtle animalic undertow. As it develops, a surprising floralcy emerges – imagine a mechanized rose with gears instead of petals. The dry-down reveals a musky-woody character with lingering citrus facets, creating an intriguing tension between natural and synthetic impressions.
In Famous Fragrances
Fragrance associations may not reflect actual formulations.
Used as the sole active ingredient to showcase its transformative properties, creating a scent that changes perception based on skin chemistry and environmental factors.
Employed as a futuristic green note modifier, adding depth and modernity to the composition’s hyper-realistic foliage accord.
Chemistry, Properties & Perfumer Guide
The Chemistry
10-Dodecen-3-one, 5-hydroxy-7,11-dimethyl- belongs to the class of unsaturated hydroxy ketones. Its synthesis typically involves controlled oxidation of appropriate precursors under mild conditions to preserve the delicate double bond. The molecule’s stereochemistry significantly impacts its odor profile, with different enantiomers exhibiting varying intensity and character.
Physical & Chemical Properties
| Appearance | Colorless to pale yellow liquid |
|---|---|
| Solubility | Soluble in alcohol and oils |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Fine Fragrance | 0.5-2% | Up to 5% | Used as a special effect ingredient |
| Functional Fragrance | 0.1-0.5% | Up to 1% | Limited use due to intensity |
Classic Accords
Tip: Use sparingly in floral bases to add dimensionality without overpowering.
Alternatives & Comparisons
Offers similar floral-metallic characteristics but with better stability in formulations requiring higher pH.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
Not currently restricted by IFRA standards.
RIFM Assessment
Under evaluation by RIFM, preliminary data suggests moderate skin sensitization potential.
Sustainability
As a synthetic material, this compound avoids natural resource depletion but requires energy-intensive manufacturing processes. Its high potency means minimal quantities are needed, reducing overall environmental impact per unit of fragrance.
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References
- Arctander, S. (1969). Perfume and Flavor Chemicals. Montclair, NJ.
Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.
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