2′-Acetonaphthone, 1′,2′,3′,4′,5′,6′,7′,8′-octahydro-1′,2′,8′,8′-tetramethyl- (CAS 108982-45-2) — Woody Base Note Fragrance Ingredient

ByThe Good Scents
Woody · Musky

2'-Acetonaphthone, 1',2',3',4',5',6',7',8'-octahydro-1',2',8',8'-tetramethyl-

CAS 108982-45-2

Origin
synthetic
Note
Base
IFRA
Use with awareness
Data as of: Apr 2026

What Is 2'-Acetonaphthone, 1',2',3',4',5',6',7',8'-octahydro-1',2',8',8'-tetramethyl-?

This synthetic molecule is primarily encountered in specialty fragrances and industrial applications. While not common in consumer products, it serves as a building block for creating unique scent profiles. Its importance lies in enabling perfumers to craft novel accords that cannot be achieved with natural ingredients alone.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
⚠ Limited safety data available
⚠ Potential skin sensitizer
CAS
108982-45-2
Formula
Mixture
MW
Variable
Odor Family
Woody · Musky
Layer 1 · Enthusiast

What Does 2'-Acetonaphthone, 1',2',3',4',5',6',7',8'-octahydro-1',2',8',8'-tetramethyl- Smell Like?

This synthetic ingredient exhibits a complex olfactory profile that evolves subtly over time. Initially presenting with a sharp, almost metallic edge, it gradually reveals underlying woody and slightly musky characteristics. The dry-down phase is characterized by a persistent, faintly sweet aroma with a hint of smokiness.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

2′-Acetonaphthone is a synthetic aromatic compound belonging to the ketone class. Its structure features a naphthalene core with an acetyl substituent, contributing to its unique olfactory properties. The molecule’s stability and volatility make it suitable for use in fragrance applications where longevity is desired.

Physical & Chemical Properties

Boiling PointNot available
DensityNot available

Perfumer Guide

Note Position
Base
Volatility
Low (hours)
Blending
Moderate
ApplicationTypical %RangeNotes
Industrial Fragrance1-3%Up to 5%Used for creating unique base notes

Classic Accords

Tip: Use sparingly to add depth and complexity to synthetic woody accords.

Alternatives & Comparisons

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No specific IFRA restrictions identified.

RIFM Assessment

No RIFM safety assessment data available.

Sustainability

As a synthetic molecule, its production involves petrochemical-derived precursors. The environmental impact depends on manufacturing processes and waste management practices.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Ingredient Data Sheet

    CAS 108982-45-2
    Data Sources & Attribution
    Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

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