2-Acetyl-3-Ethylpyrazine (CAS 32974-92-8) — Mid Note Fragrance Ingredient



gourmand

2-Acetyl-3-Ethylpyrazine

CAS 32974-92-8

Note
mid
Volatility
medium
MW
150.2
Data as of: Jun 2026

What Is 2-Acetyl-3-Ethylpyrazine?

2-Acetyl-3-Ethylpyrazine (CAS 32974-92-8) is an aroma chemical used as a fragrance and flavour ingredient. Its odour is described as bakery, sweet and fish, placing it within the gourmand family as a mid note with medium volatility. With a molecular weight of 150.2 (formula C8H10N2O), it is handled by perfumers as a building block for compositions where a bakery character is desired. The data below is compiled from public chemical and regulatory sources.

Safety Profile

HANDLE WITH CARE

Generally safeUse with awarenessProfessional use
CAS
32974-92-8
Formula
C8H10N2O
MW
150.2
InChIKey
PPJSYGVFDJEMRP-UHFFFAOYSA-N
2-Acetyl-3-Ethylpyrazine 2D structure

2-Acetyl-3-Ethylpyrazine
C8H10N2O
Layer 1 · Enthusiast

What Does 2-Acetyl-3-Ethylpyrazine Smell Like?

The odour profile of 2-Acetyl-3-Ethylpyrazine is reported as bakery, sweet, fish, garlic, spices, cold, sour, burnt, acid, warm, musky, sweaty, ammonia/urinous, decayed, wood, grass, flower, chemical, edible. The dominant facet is its bakery character, with the remaining notes adding nuance and complexity. As a mid note it contributes to the heart of a fragrance. Perceived intensity and exact character depend on concentration, the carrier and the surrounding accord.

Scent Profile

Profile derived from public odour-descriptor data; relative, not absolute.

Layer 2

Chemistry & Properties

The Chemistry

2-Acetyl-3-Ethylpyrazine has the molecular formula C8H10N2O and a molecular weight of 150.2 g/mol. Its canonical SMILES representation is CCC1=C(N=CC=N1)C(C)=O. Its reported log P (XLogP) of 1.24 indicates a moderately polar molecule, which informs how it partitions in a formula. Physical constants below are drawn from PubChem and EPA CompTox public datasets.

Physical & Chemical Properties

Molecular Weight 150.2 g/mol
Boiling Point 247.3 °C
Melting Point 68.93 °C
Flash Point 91.53 °C
Density 1.07 g/cm³
Vapor Pressure 0.06042 mmHg
Water Solubility 0.07111 g/L
XLogP 1.24

Perfumer Guide

Note Position
Mid
Volatility
Medium
Primary Odour
Bakery

Alternatives & Comparisons

Ingredients occupying a similar odour space — useful as substitutes or companions when 2-Acetyl-3-Ethylpyrazine is unavailable or restricted.

1
Isopentylamine CAS 107-85-7

Shares bakery, sweet, fish character — a candidate substitute or companion in the same odour space.

2
Ethyl 3-(Furfurylthio) Propionate CAS 94278-27-0

Shares bakery, sweet, fish character — a candidate substitute or companion in the same odour space.

3
Pyrazine CAS 290-37-9

Shares bakery, sweet, fish character — a candidate substitute or companion in the same odour space.

Layer 3

Safety & Regulatory

⚠ Regulatory Disclaimer

General reference only. IFRA, REACH and EU Cosmetics Regulation standards update periodically. Consult the current IFRA Standards Library before formulating. Not legal or regulatory advice.

IFRA Status

No IFRA restriction recorded in the data set. This is not a guarantee of unrestricted status — always confirm against the current IFRA Standards Library.

GHS Classification

Signal word: Warning

H302H312H332
Formulating with 2-Acetyl-3-Ethylpyrazine?

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References & Sources

  1. PubChem Compound Summary (NIH) — search by InChIKey
  2. EPA CompTox Chemicals Dashboard — physicochemical & fate data
  3. IFRA Standards Library (49th / 51st Amendment)
Sources: PubChem (NIH) · EPA CompTox · IFRA Standards Library · public GHS classification. Odour descriptors are original editorial summaries of public profiles, not reproduced from any single proprietary source.

Data: PubChem (NIH), EPA CompTox, IFRA. Last reviewed: Jun 2026.

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