2-Butanone, phenylhydrazone (CAS 1129-62-0) — Green Specialty Note Fragrance Ingredient

Green · Woody

2-Butanone, phenylhydrazone

CAS 1129-62-0

Origin
synthetic
Note
Specialty
IFRA
Professional use
Data as of: Apr 2026

What Is 2-Butanone, phenylhydrazone?

2-Butanone, phenylhydrazone is a synthetic chemical used in specialized fragrance formulations. It’s not commonly encountered in consumer products but may appear in niche perfumery. This ingredient matters because it represents a class of fragrance molecules that can impart unique olfactory characteristics, though its use is limited due to safety considerations.

Safety Profile

PROFESSIONAL USE
Generally safeUse with awarenessProfessional use
Professional formulation required
Potential sensitizer – handle with care
CAS
1129-62-0
Formula
Mixture
MW
Variable
Odor Family
Green · Woody
Layer 1 · Enthusiast

What Does 2-Butanone, phenylhydrazone Smell Like?

2-Butanone, phenylhydrazone has a sharp, chemical odor with green, slightly animalic undertones. The initial impression is intensely synthetic, evolving into a more subdued, dry woodiness. The dry-down reveals faint phenolic characteristics that linger close to the skin. Performance is moderate, with projection diminishing quickly but leaving a subtle trace for several hours.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Layer 2

2D Molecular Structure

Phenylhydrazone-2-butanone

SMILES: CC\C(C)=N\NC1=CC=CC=C1

Chemistry, Properties & Perfumer Guide

The Chemistry

2-Butanone, phenylhydrazone belongs to the hydrazone class of compounds, formed by the condensation of 2-butanone with phenylhydrazine. These compounds are typically synthesized in laboratory settings and are not found in nature. The phenylhydrazone moiety contributes to both the molecular stability and the distinct olfactory profile of this material.

Physical & Chemical Properties

Molecular WeightN/A
Boiling PointN/A

Perfumer Guide

Note Position
Specialty
Volatility
Moderate
Blending
Limited
ApplicationTypical %RangeNotes
Experimental Perfumery<0.5%Trace amountsUsed for specific olfactory effects

Classic Accords

Tip: Use in minute quantities and always with proper safety evaluation.

Alternatives & Comparisons

1
Methyl ethyl ketone CAS 78-93-3

A simpler ketone with less safety concerns for similar applications.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not currently listed in IFRA standards.

GHS Classification

H302 Harmful if swallowed H312 Harmful in contact with skin

RIFM Assessment

No RIFM safety assessment currently available.

Sustainability

This synthetic compound has minimal environmental impact when properly handled, but requires energy-intensive laboratory synthesis. Disposal should follow hazardous chemical protocols.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Physicochemical Properties

    DTXSID: DTXSID9051585

    Physical Properties

    Molecular Weight 162.236 g/mol🔬 EPA CompTox
    Density 1.006 g/cm^3📊 OPERA
    Boiling Point 219.09 °C📊 OPERA
    Melting Point 65.315 °C📊 OPERA
    Flash Point 100.499 °C📊 OPERA
    Refractive Index 1.512 Dimensionless📊 OPERA
    Molar Volume 172.627 cm^3/mol📊 OPERA

    Partition & Solubility

    LogP (Octanol-Water) 2.585 Log10 unitless📊 OPERA
    LogD (pH 5.5) 1.482 Log10 unitless📊 OPERA
    LogD (pH 7.4) 2.35 Log10 unitless📊 OPERA
    LogKoa (Octanol-Air) 4.52 Log10 unitless📊 OPERA
    Water Solubility 0.003 mol/L📊 OPERA
    Henry's Law Constant 0 atm-m3/mole📊 OPERA

    Transport Properties

    Vapor Pressure 0.068 mmHg📊 OPERA
    Surface Tension 31.861 dyn/cm📊 OPERA

    Molecular Descriptors

    Topological Polar Surface Area 24.39 Ų💻 Computed
    H-Bond Donors 1 count💻 Computed
    H-Bond Acceptors 2 count💻 Computed
    Rotatable Bonds 3 count💻 Computed
    Aromatic Rings 1 count💻 Computed
    Molar Refractivity 51.818 cm^3/mol📊 OPERA
    Polarizability 20.542 Å^3📊 OPERA

    Data Sources:

    🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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