9,10-Anthracenedione, 1,4-diamino-2,3-diphenoxy- (CAS 6408-72-6) — Citrus N/A Note Fragrance Ingredient

Citrus · Floral

9,10-Anthracenedione, 1,4-diamino-2,3-diphenoxy-

CAS 6408-72-6

Origin
synthetic
Note
N/A
IFRA
Professional use
Data as of: Apr 2026

What Is 9,10-Anthracenedione, 1,4-diamino-2,3-diphenoxy-?

1,4-diamino-2,3-diphenoxy-9,10-anthracenedione is a synthetic dye compound primarily used in industrial applications. Consumers may encounter it in specialized inks or colorants, though it is not commonly found in consumer products. This anthraquinone derivative is valued for its intense color properties rather than fragrance applications. Its molecular structure makes it photostable and resistant to fading, which is important for long-lasting coloration in technical uses.

Safety Profile

PROFESSIONAL USE
Generally safeUse with awarenessProfessional use
Industrial handling precautions required
Not approved for cosmetic use
CAS
6408-72-6
Formula
Mixture
MW
Variable
Odor Family
Citrus · Floral
Layer 1 · Enthusiast

What Does 9,10-Anthracenedione, 1,4-diamino-2,3-diphenoxy- Smell Like?

This compound is not characterized by any significant odor profile, as it is primarily developed for its colorant properties rather than fragrance applications. The molecular structure suggests potential aromatic phenolic notes if volatilized, but the compound’s low volatility and high molecular weight prevent any notable olfactory characteristics from being perceptible in standard conditions.

Layer 2

2D Molecular Structure

9,10-Anthracenedione, 1,4-diamino-2,3-diphenoxy-

SMILES: NC1=C2C(=O)C3=C(C=CC=C3)C(=O)C2=C(N)C(OC2=CC=CC=C2)=C1OC1=CC=CC=C1

Chemistry, Properties & Perfumer Guide

The Chemistry

1,4-diamino-2,3-diphenoxy-9,10-anthracenedione belongs to the anthraquinone class of compounds, known for their dye properties. The molecule features a central anthracenedione core with amino and phenoxy substituents that enhance its color intensity. Synthesis typically involves multi-step reactions starting from anthraquinone precursors, with careful control of substitution patterns. The diphenoxy groups contribute to the compound’s solubility profile while the diamino groups influence its chromophoric properties.

Physical & Chemical Properties

Molecular ClassAnthraquinone derivative
Primary UseIndustrial dye

Perfumer Guide

Note Position
N/A
Volatility
N/A
Blending
N/A
ApplicationTypical %RangeNotes
Industrial DyesSpecialized useFormula-dependentNot for fragrance applications

Classic Accords

Tip: This compound is not suitable for perfumery applications.

Alternatives & Comparisons

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not evaluated by IFRA – industrial use only

RIFM Assessment

No RIFM assessment available – industrial chemical

Sustainability

As an industrial synthetic compound, environmental considerations focus on manufacturing waste streams and potential persistence. The anthraquinone structure may resist biodegradation. Proper disposal procedures should be followed to prevent environmental contamination. No natural sourcing alternatives exist for this specialized synthetic dye.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Physicochemical Properties

    DTXSID: DTXSID1064320

    Physical Properties

    Molecular Weight 422.44 g/mol🔬 EPA CompTox
    Density 0.996 g/cm^3🔬 EPA CTX
    Boiling Point 539.06 °C🔬 EPA CTX
    Melting Point 191.5 °C🔬 EPA CTX
    Flash Point 284.139 °C📊 OPERA
    Refractive Index 1.717 Dimensionless📊 OPERA
    Molar Volume 304.8 cm^3/mol📊 OPERA

    Partition & Solubility

    LogP (Octanol-Water) 5.172 Log10 unitless🔬 EPA CTX
    LogD (pH 5.5) 4.395 Log10 unitless📊 OPERA
    LogD (pH 7.4) 5.075 Log10 unitless📊 OPERA
    LogKoa (Octanol-Air) 9.68 Log10 unitless📊 OPERA
    Water Solubility 0 mol/L🔬 EPA CTX
    Henry's Law Constant 0 atm-m3/mole📊 OPERA

    Transport Properties

    Vapor Pressure 0 mmHg📊 OPERA
    Surface Tension 68.08 dyn/cm📊 OPERA

    Molecular Descriptors

    Topological Polar Surface Area 104.64 Ų💻 Computed
    H-Bond Donors 2 count💻 Computed
    H-Bond Acceptors 6 count💻 Computed
    Rotatable Bonds 4 count💻 Computed
    Aromatic Rings 4 count💻 Computed
    Molar Refractivity 120.028 cm^3/mol📊 OPERA
    Polarizability 47.583 Å^3📊 OPERA

    Data Sources:

    🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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