Anisyl alcohol (o-,m-,p-) (CAS 1331-81-3) — Sweet Middle Note Fragrance Ingredient

Sweet · Floral

Anisyl alcohol (o-,m-,p-)

CAS 1331-81-3

Origin
synthetic
Note
Middle
IFRA
Generally safe
Data as of: Apr 2026

What Is Anisyl alcohol (o-,m-,p-)?

Anisyl alcohol is a synthetic fragrance compound with a sweet, floral-anisic aroma. It’s commonly found in perfumes, soaps, and cosmetic products where a soft powdery character is desired. This ingredient matters because it adds a delicate, vanilla-like nuance to floral compositions while being more stable than some natural alternatives.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
No major restrictions
Potential mild skin sensitivity
CAS
1331-81-3
Formula
Mixture
MW
Variable
Odor Family
Sweet · Floral
Layer 1 · Enthusiast

What Does Anisyl alcohol (o-,m-,p-) Smell Like?

Anisyl alcohol unfolds with an initial sweet-powdery burst reminiscent of marshmallow and vanilla pods. The heart reveals a delicate floral character akin to lilac and heliotrope, with a subtle anisic undertone that never dominates. As it dries down, it leaves a soft musky-powdery trail that blends seamlessly with other florals. The overall effect is like catching whiffs of a vintage face powder infused with almond blossoms.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Shalimar(Guerlain, 1925)

Used to soften the citrus-vanilla transition, adding powdery depth that bridges the bergamot top with the balsamic base.

L'Heure Bleue(Guerlain, 1912)

Contributes to the twilight floral effect, enhancing the heliotrope and violet notes with its sweet-powdery character.

Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

Anisyl alcohol refers to three isomeric methoxybenzyl alcohols (ortho-, meta-, and para-). The para-isomer is most commonly used in perfumery. Synthesized via reduction of anisaldehyde or methylation of hydroxybenzyl alcohol, it belongs to the aromatic alcohol class. The methoxy group’s position significantly impacts odor profile – the para-isomer being most floral, while meta- has sharper anisic qualities.

Physical & Chemical Properties

Boiling Point259 °C
Density1.11 g/cm³

Perfumer Guide

Note Position
Middle
Volatility
Moderate (2-6 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-3%Up to 5%Powdery floral modifier
Soap0.5-1%Up to 2%Stable in alkaline systems

Classic Accords

Tip: Use to round out sharp floral notes and add diffusion to powdery accords.

Alternatives & Comparisons

1
Heliotropin CAS 120-57-0

For stronger powdery-cherry effects, though less sweet and more almond-like in character.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No IFRA restrictions (as of Amendment 51).

RIFM Assessment

Evaluated as safe for current use levels in fragrance applications.

Sustainability

Synthetic production avoids agricultural impacts. Typically manufactured from petrochemical precursors, though some green chemistry routes exist using guaiacol from lignin. Energy-intensive purification steps are the main environmental concern.

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References

  1. Bauer et al. (2001). Common Fragrance and Flavor Materials. Wiley-VCH.

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Ingredient Data Sheet

CAS 1331-81-3

Regulatory Status

IFRA ListedYes — see IFRA Standards for category limits⚖️ IFRA 51
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

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