Benzyl trans-2-methyl-2-butenoate (CAS 37526-88-8) — Sweet Top to middle Note Fragrance Ingredient

Sweet · Floral

Benzyl trans-2-methyl-2-butenoate

CAS 37526-88-8

Origin
synthetic
Note
Top to middle
IFRA
Generally safe
Data as of: Apr 2026

What Is Benzyl trans-2-methyl-2-butenoate?

Benzyl trans-2-methyl-2-butenoate is a synthetic fragrance ingredient used in perfumes and scented products. It contributes to fruity, floral, and slightly woody accords. You’ll encounter it in fine fragrances, body care products, and some household cleaners. This ester compound matters because it adds diffusion and brightness to fragrance compositions, often enhancing fruity top notes without being overpowering.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
No major restrictions in current IFRA guidelines
Limited toxicological data available
CAS
37526-88-8
Formula
Mixture
MW
Variable
Odor Family
Sweet · Floral
Layer 1 · Enthusiast

What Does Benzyl trans-2-methyl-2-butenoate Smell Like?

Benzyl trans-2-methyl-2-butenoate opens with a vibrant, ripe strawberry-like fruitiness that quickly reveals a jammy, almost wine-like depth. The heart develops into a soft floral character reminiscent of gardenia petals dipped in honey, while the dry-down leaves a whisper of clean, slightly woody musk. Unlike simpler fruity esters, this molecule has remarkable persistence and evolves beautifully on skin, maintaining its character without turning cloying.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Tendre Poison(Dior, 1994)

Used here as a fruity-floral bridge between the bright top notes and deeper woody base. Its persistence helps maintain the fragrance’s signature ‘poisoned fruit’ effect throughout wear.

Lolita Lempicka(Lolita Lempicka, 1997)

Contributes to the licorice-anise fantasy with its unusual fruity-winey facet, adding complexity to the gourmand structure without being identifiably fruity.

Layer 2

2D Molecular Structure

Benzyl (2E)-2-methylbut-2-enoate

SMILES: C\C=C(/C)C(=O)OCC1=CC=CC=C1

Chemistry, Properties & Perfumer Guide

The Chemistry

Benzyl trans-2-methyl-2-butenoate is an ester formed from benzyl alcohol and trans-2-methyl-2-butenoic acid (tiglic acid). The trans configuration at the double bond is crucial for its odor profile. Industrial synthesis typically involves acid-catalyzed esterification under controlled conditions to prevent isomerization. This chiral molecule exists as a single enantiomer in commercial production, with the (E)-configuration being odor-active while the (Z)-isomer is typically odorless.

Physical & Chemical Properties

AppearanceColorless to pale yellow liquid
Boiling Point~260 °C (estimated)
Density~1.01 g/cm³ (estimated)

Perfumer Guide

Note Position
Top to middle
Volatility
Medium (2-4 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance0.5-2%Up to 5%Adds fruity complexity without dominating
Body Care0.1-0.5%Up to 1%Provides long-lasting fruity notes

Classic Accords

Tip: Use with ionones to create dimensional fruity-floral effects that resist turning candy-like.

Alternatives & Comparisons

1
Benzyl acetate CAS 140-11-4

For simpler, more straightforward fruity notes with less persistence. Prefer when a cleaner jasmine effect is needed without winey undertones.

2
Ethyl tiglate CAS 5837-78-5

When a brighter, more diffusive fruity note is required without the benzyl alcohol-derived floralcy.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not currently restricted under IFRA standards. Listed in IFRA Transparency List with no usage limits specified.

RIFM Assessment

Under evaluation by RIFM. Preliminary data suggests low sensitization potential.

Sustainability

As a synthetic material, benzyl trans-2-methyl-2-butenoate has consistent quality and doesn’t depend on agricultural production. The benzyl alcohol component can be derived from renewable toluene sources. Current production methods have moderate energy requirements but generate minimal hazardous waste compared to some other ester syntheses.

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References

  1. Bauer et al. (2001). Common Fragrance and Flavor Materials. Wiley-VCH.

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Ingredient Data Sheet

CAS 37526-88-8

Physical Properties

Molecular Weight190.24 g/mol🔬 PubChem
LogP (Octanol-Water)2.8🔬 PubChem
Boiling Point262 °C🔬 EPA CompTox
Vapor Pressure0.0257 mmHg @ 25°C📊 OPERA
Flash Point135.9 °C🔬 EPA CompTox
Involatility Index0.002💻 Calculated
log Kp (skin permeability)-1.872💻 Calculated
SMILESCC=C(C)C(=O)OCC1=CC=CC=C1🔬 PubChem

Volatility & Performance

Fragrance NoteHeart💻 Calculated
Volatility ClassVery slow💻 Calculated
Persistence Score2.9 / 5💻 Calculated

Odor & Flavor

Primary Descriptorsmushroomrose• leffingwell
Functional Groupsesteretheralkenearomatic💻 RDKit
“Peculiar fungus-like, mushroom-type odor with a rosy undertone.”📖 Arctander
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

Physicochemical Properties

DTXSID: DTXSID3047130

Physical Properties

Molecular Weight 190.242 g/mol🔬 EPA CompTox
Density 1.035 g/cm^3🔬 EPA CTX
Boiling Point 266.959 °C📊 OPERA
Melting Point 8.829 °C📊 OPERA
Flash Point 136.74 °C📊 OPERA
Refractive Index 1.517 Dimensionless📊 OPERA
Molar Volume 185.176 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 3.112 Log10 unitless📊 OPERA
LogD (pH 5.5) 3.112 Log10 unitless📊 OPERA
LogD (pH 7.4) 3.112 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 6.11 Log10 unitless📊 OPERA
Water Solubility 0.002 mol/L📊 OPERA
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0.012 mmHg📊 OPERA
Surface Tension 35.558 dyn/cm📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 26.3 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 2 count💻 Computed
Rotatable Bonds 3 count💻 Computed
Aromatic Rings 1 count💻 Computed
Molar Refractivity 56.009 cm^3/mol📊 OPERA
Polarizability 22.204 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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