Cinnamic Acid (CAS 621-82-9) — Balsamic Base Note Fragrance Ingredient

Cinnamic Acid

CAS 621-82-9

Origin
Note
IFRA
Use with awareness
Data as of: Mar 2026

What Is Cinnamic Acid?

Cinnamic acid is a naturally occurring compound found in cinnamon bark and other plants, giving them their characteristic warm, spicy aroma. It’s commonly encountered in perfumes, flavored foods, and some cosmetic products. This ingredient matters because it serves as a building block for many fragrance molecules and contributes to warm, balsamic notes in perfumery. Its versatility allows perfumers to create everything from spicy oriental scents to sweet gourmand accords.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
Approved for use in cosmetics
Potential skin sensitizer at high concentrations
CAS
621-82-9
Formula
Mixture
MW
Variable
Odor Family
Layer 1 · Enthusiast

What Does Cinnamic Acid Smell Like?

Cinnamic acid presents a warm, honeyed balsamic character with distinct spicy-cinnamon undertones. Upon first application, it reveals a slightly sharp, phenolic edge that quickly mellows into a rich, resinous heart. The dry-down evolves into a soft vanillic sweetness reminiscent of benzoin, with persistent woody-ambery facets. In blends, it adds depth and warmth, acting as a natural bridge between bright top notes and deep base accords. The aroma profile combines elements of dried fruits, faint floral nuances, and a distinctive cinnamon stick character that becomes creamier over time.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Shalimar(Guerlain, 1925)

Used as a key modifier in the vanilla-amber base, contributing to the legendary oriental warmth and helping bridge the citrus top notes to the resinous heart.

Cinnabar(Estée Lauder, 1978)

Provides authentic cinnamon-spice character in this rich oriental, blending seamlessly with clove and patchouli to create a warm, festive aura.

Opium(Yves Saint Laurent, 1977)

Contributes to the complex spice accord, adding balsamic depth that complements the myrrh and vanilla in this iconic oriental fragrance.

Obsession(Calvin Klein, 1985)

Works in the amber base to enhance warmth and longevity, pairing with sandalwood to create a sensual, slightly gourmand dry-down.

Joop! Homme(Joop!, 1989)

Provides subtle spicy warmth that balances the sweet floralcy in this powerful masculine fragrance, adding sophistication to the vanilla base.

Layer 2

2D Molecular Structure

Cinnamic acid

SMILES: OC(=O)C=CC1=CC=CC=C1

Chemistry, Properties & Perfumer Guide

The Chemistry

Cinnamic acid is an unsaturated carboxylic acid belonging to the phenylpropanoid class of organic compounds. Naturally occurring as both trans- and cis-isomers, with the trans-form being more common and stable. Industrially produced via Perkin synthesis from benzaldehyde and acetic anhydride, or through microbial fermentation of L-phenylalanine. The molecule’s conjugated π-system contributes to its UV absorption properties and chemical reactivity. As a precursor, it’s hydrogenated to produce hydrocinnamic acid or esterified to create important fragrance materials like cinnamyl acetate and methyl cinnamate.

Physical & Chemical Properties

Boiling Point300 °C
Melting Point133 °C
Density1.248 g/cm³
Flash Point>110 °C
Vapor Pressure0.000126 mmHg at 25°C
SolubilitySlightly soluble in water, soluble in ethanol and ether
AppearanceWhite to pale yellow crystalline powder

Perfumer Guide

Note Position
Middle to base
Volatility
Medium (2-6 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance0.5-2%Up to 3%Used for warm spicy accents
Soaps0.1-0.5%Up to 1%Adds persistent balsamic character
Detergents0.05-0.2%Up to 0.5%Used sparingly for warmth
Candles1-3%Up to 5%Provides good heat stability

Classic Accords

+ Vanilla + Benzoin = Oriental Base + Clove + Orange = Spiced Citrus + Patchouli + Amber = Warm Woody

Tip: Use in trace amounts with citrus top notes to prevent pH-related discoloration in clear products.

Alternatives & Comparisons

1
Hydrocinnamic Acid CAS 501-52-0

Less spicy but more stable alternative with similar balsamic character, preferred in formulations requiring pH neutrality.

2
Methyl Cinnamate CAS 103-26-4

Esterified form with stronger fruity-floral notes and better solubility, used when a sweeter profile is desired.

3
Cinnamyl Alcohol CAS 104-54-1

Alcohol derivative with softer, more floral character and reduced risk of skin sensitization.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. IFRA, REACH, EU Cosmetics Regulation standards update periodically. Consult current IFRA Standards Library before formulating. Not legal or regulatory advice.

IFRA Status

Not currently restricted by IFRA standards. Listed as safe when used within typical fragrance concentrations.

EU Allergen Declaration

Not listed as an EU allergen under Regulation (EC) No 1223/2009.

GHS Classification

H315 Causes skin irritation H319 Causes serious eye irritation

RIFM Assessment

RIFM evaluation confirms safe use at current industry levels with no significant risk of phototoxicity or systemic effects.

Sustainability

Primarily synthesized from petrochemical sources, though natural extraction from cinnamon bark or storax resin is possible but less economical. Production via biofermentation using engineered yeast strains shows promise for more sustainable future production. Biodegradability studies show moderate environmental persistence.

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References

  1. Bickers et al. (2005). The safety assessment of fragrance materials. Regulatory Toxicology and Pharmacology. PMID 16188365
  2. Bauer et al. (2008). Common Fragrance and Flavor Materials. Wiley-VCH.
  3. PubChem Compound Summary for CID 444539 PubChem CID 444539

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Mar 2026.

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Physicochemical Properties

DTXSID: DTXSID40110056

Physical Properties

Molecular Weight 148.161 g/mol🔬 EPA CompTox
Density 1.174 g/cm^3📊 OPERA
Boiling Point 281.039 °C📊 OPERA
Melting Point 133.167 °C🔬 EPA CTX
Flash Point 172 °C🔬 EPA CTX
Refractive Index 1.616 Dimensionless📊 OPERA
Molar Volume 125.035 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 2.12 Log10 unitless🔬 EPA CTX
LogD (pH 5.5) 0.895 Log10 unitless📊 OPERA
LogD (pH 7.4) -0.947 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 7.63 Log10 unitless📊 OPERA
Water Solubility 0.004 mol/L🔬 EPA CTX
Henry's Law Constant 0 atm-m3/mole🔬 EPA CTX

Transport Properties

Vapor Pressure 0.002 mmHg📊 OPERA
Viscosity 5.017 cP📊 OPERA
Surface Tension 44.475 dyn/cm📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 37.3 Ų💻 Computed
H-Bond Donors 1 count💻 Computed
H-Bond Acceptors 1 count💻 Computed
Rotatable Bonds 2 count💻 Computed
Aromatic Rings 1 count💻 Computed
Molar Refractivity 43.707 cm^3/mol📊 OPERA
Polarizability 17.327 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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