Citronellyl ethyl oxalate (CAS 60788-25-2) — Floral Middle Note Fragrance Ingredient

Floral · Sweet

Citronellyl ethyl oxalate

CAS 60788-25-2

Origin
synthetic
Note
Middle
IFRA
Generally safe
Data as of: Apr 2026

What Is Citronellyl ethyl oxalate?

Citronellyl ethyl oxalate is a synthetic fragrance ingredient used to add fresh, floral, and slightly fruity nuances to perfumes and scented products. It’s commonly found in soaps, detergents, and fine fragrances. This ester contributes to the complexity and longevity of scents, making it valuable in modern perfumery.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
Safe in regulated products
Check for individual sensitivities
CAS
60788-25-2
Formula
Mixture
MW
Variable
Odor Family
Floral · Sweet
Layer 1 · Enthusiast

What Does Citronellyl ethyl oxalate Smell Like?

Citronellyl ethyl oxalate opens with a bright, fresh floralcy reminiscent of dewy rose petals and citrus zest. As it evolves, it reveals a subtle fruity undertone, like ripe peaches drizzled with honey. The dry-down is clean and slightly green, akin to freshly crushed leaves. Its behavior is linear yet nuanced, making it versatile in compositions.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Eau de Soleil Blanc(Tom Ford, 2016)

Used to enhance the floral freshness and add a subtle fruity nuance, complementing the coconut and white flowers.

Chance Eau Tendre(Chanel, 2010)

Adds a crisp, floral lift to the grapefruit and jasmine heart, creating a modern freshness.

Layer 2

2D Molecular Structure

3,7-Dimethyloct-6-en-1-yl ethyl ethanedioate

SMILES: CCOC(=O)C(=O)OCCC(C)CCC=C(C)C

Chemistry, Properties & Perfumer Guide

The Chemistry

Citronellyl ethyl oxalate is an ester formed from citronellol and ethyl oxalate. It belongs to the class of synthetic fragrance compounds designed to mimic natural floral notes. Its synthesis typically involves esterification under controlled conditions to ensure purity and consistency. The molecule’s stability and low volatility make it ideal for lasting floral accords.

Physical & Chemical Properties

Boiling PointN/A
DensityN/A

Perfumer Guide

Note Position
Middle
Volatility
Medium (2-4 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-5%Up to 10%Adds floral freshness
Soaps & Detergents0.5-2%Up to 5%Enhances clean notes

Classic Accords

Tip: Use in floral compositions to add a fresh, slightly fruity lift.

Alternatives & Comparisons

1
Citronellol CAS 106-22-9

A more direct floral note, less fruity and more rosy.

2
Ethyl oxalate CAS 95-92-1

Provides a sharper, greener edge without the floralcy.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No IFRA restrictions currently apply.

EU Allergen Declaration

Not listed as an EU allergen.

RIFM Assessment

RIFM assessment pending. Generally recognized as safe for current usage levels.

Sustainability

Synthetic production ensures consistent quality and reduces reliance on natural resources. The process is optimized for minimal environmental impact, with waste management protocols in place.

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References

  1. PubChem Compound Summary for Citronellyl ethyl oxalate PubChem

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Ingredient Data Sheet

CAS 60788-25-2

Physical Properties

Molecular Weight256.34 g/mol🔬 PubChem
LogP (Octanol-Water)4.4🔬 PubChem
Boiling Point280 °C🔬 EPA CompTox
Vapor Pressure0.0013 mmHg @ 25°C📊 OPERA
Flash Point136.1 °C🔬 EPA CompTox
Involatility Index0.0001💻 Calculated
log Kp (skin permeability)-1.14💻 Calculated
SMILESCCOC(=O)C(=O)OCCC(C)CCC=C(C)C🔬 PubChem

Volatility & Performance

Fragrance NoteBase💻 Calculated
Volatility ClassVery slow💻 Calculated
Persistence Score6.9 / 5💻 Calculated

Odor & Flavor

Primary Descriptorsfloralsweet• leffingwell
Functional Groupsesteretheralkene💻 RDKit
“Sweet, floral-musky odor with notes resembling those of Labdanum and Ambrette seed, or the sweet notes of Ambregris.”📖 Arctander

Sensory Thresholds

Odor Detection Threshold0.014 ppm📖 van Gemert
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

Physicochemical Properties

DTXSID: DTXSID8052275

Physical Properties

Molecular Weight 256.342 g/mol🔬 EPA CompTox
Density 0.977 g/cm^3📊 OPERA
Boiling Point 300.329 °C📊 OPERA
Melting Point -20.046 °C📊 OPERA
Flash Point 127.068 °C📊 OPERA
Refractive Index 1.453 Dimensionless📊 OPERA
Molar Volume 260.387 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 3.43 Log10 unitless📊 OPERA
LogD (pH 5.5) 3.43 Log10 unitless📊 OPERA
LogD (pH 7.4) 3.43 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 7.45 Log10 unitless📊 OPERA
Water Solubility 0.002 mol/L📊 OPERA
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0.001 mmHg📊 OPERA
Viscosity 3.518 cP📊 OPERA
Surface Tension 30.653 dyn/cm📊 OPERA
Thermal Conductivity 145.78 mW/(m*K)📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 52.6 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 4 count💻 Computed
Rotatable Bonds 7 count💻 Computed
Aromatic Rings 0 count💻 Computed
Molar Refractivity 70.318 cm^3/mol📊 OPERA
Polarizability 27.876 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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