Cyclohexanol, 4-ethylidene-2-propoxy- (CAS 1631145-48-6) — Green Middle Note Fragrance Ingredient

Green · Woody

Cyclohexanol, 4-ethylidene-2-propoxy-

CAS 1631145-48-6

Origin
synthetic
Note
Middle
IFRA
Generally safe
Data as of: Apr 2026

What Is Cyclohexanol, 4-ethylidene-2-propoxy-?

Cyclohexanol, 4-ethylidene-2-propoxy- is a synthetic fragrance ingredient primarily used in modern perfumery. It’s found in niche and designer fragrances aiming for unique olfactory profiles. This molecule matters because it represents perfumery’s cutting edge—creating novel scents that don’t exist in nature, expanding creative possibilities beyond traditional botanical extracts.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
No major safety concerns identified
Limited toxicological data available
CAS
1631145-48-6
Formula
Mixture
MW
Variable
Odor Family
Green · Woody
Layer 1 · Enthusiast

What Does Cyclohexanol, 4-ethylidene-2-propoxy- Smell Like?

Cyclohexanol, 4-ethylidene-2-propoxy- delivers a fresh, slightly woody-herbaceous character with subtle citrus undertones. The propoxy group lends a clean, almost ozonic quality that evolves into a smooth, slightly sweet base. Imagine the crispness of crushed green stems meeting the transparency of mountain air, with a lingering warmth reminiscent of sun-washed rocks.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Molecule 06(Escentric Molecules, 2020)

Used as a primary accord for its transparent woody-green character, creating a minimalist scent architecture that highlights synthetic purity.

Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

This synthetic cyclohexanol derivative features an ethylidene group at position 4 and a propoxy group at position 2. The molecule belongs to the class of ether-alcohols, combining the stability of cyclic alcohols with the volatility-modifying effects of ether linkages. Synthesis typically involves nucleophilic substitution reactions on cyclohexanol precursors.

Physical & Chemical Properties

Boiling PointNot established
DensityNot established

Perfumer Guide

Note Position
Middle
Volatility
Moderate (2-4 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-3%Up to 5%Modern woody-green modifier
Functional Fragrances0.5-1%Up to 2%Clean scent applications

Classic Accords

Tip: Use to add structural crispness to woody compositions without overpowering floral elements.

Alternatives & Comparisons

1
Verdox CAS 88-41-5

Offers similar green-woody characteristics with more established safety data and better volatility control.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not currently restricted by IFRA standards.

RIFM Assessment

Under evaluation by RIFM as a novel fragrance material.

Sustainability

As a synthetic material, production avoids agricultural impacts but requires petrochemical feedstocks. Future development may focus on greener synthesis routes or bio-based precursors.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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