Damascone Beta (CAS 23726-93-4) — Floral Top Note Fragrance Ingredient

Damascone Beta

CAS 23726-93-4

Origin
Note
IFRA
Use with awareness
Data as of: Mar 2026

What Is Damascone Beta?

Damascone Beta is a synthetic fragrance molecule that creates rich, fruity-rosy aromas. You’ll find it in luxury perfumes, body care products, and some gourmand flavors. This ingredient matters because it adds depth and longevity to floral compositions, mimicking the natural scent of roses but with greater stability and intensity than natural extracts.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
IFRA-approved for cosmetic use
Potential sensitizer at high concentrations
CAS
23726-93-4
Formula
Mixture
MW
Variable
Odor Family
Layer 1 · Enthusiast

What Does Damascone Beta Smell Like?

Damascone Beta unfolds with an intense burst of stewed apple and plum skin, evolving into a velvety rose jam heart. The dry-down reveals honeyed tobacco nuances with a whisper of black tea tannins. Unlike fresh rose notes, it carries a decadent, almost wine-like richness that lingers on skin for hours, making it ideal for oriental and chypre compositions.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Eau Sauvage(Dior, 1966)

Used as a fruity-rosy bridge between citrus top notes and woody base, adding sophistication to this masculine classic.

No. 5 L'Eau(Chanel, 2016)

Modernizes the floral bouquet with juicy damascone facets that complement the reformulated aldehydic structure.

Portrait of a Lady(Frédéric Malle, 2010)

Amplifies the dark rose core with damascone’s jammy depth, contrasting with patchouli and incense.

Black Orchid(Tom Ford, 2006)

Provides the fruity undertone to the exotic floral accord, enhancing the perfume’s gourmand sensuality.

Rose 31(Le Labo, 2006)

Damascone Beta tempers the spice notes with rosy sweetness, creating a gender-fluid woody rose.

Layer 2

2D Molecular Structure

beta-Damascenone

SMILES: C\C=C\C(=O)C1=C(C)C=CCC1(C)C

Chemistry, Properties & Perfumer Guide

The Chemistry

Damascone Beta belongs to the ionone/damascone family of cyclic terpenoid ketones. While α-damascone occurs naturally in rose oil, the β isomer is primarily synthetic. Industrial production typically involves acid-catalyzed cyclization of pseudoionone derivatives. The molecule’s potency stems from its conjugated double bond system and methyl group positioning, which create exceptional olfactory persistence. Chirality significantly impacts scent profile – the (R)-enantiomer exhibits stronger fruity character than the (S)-form.

Physical & Chemical Properties

Boiling Point~250 °C (estimated)
Density~0.93 g/cm³ (estimated)
Vapor PressureLow (persistent)
SolubilitySoluble in ethanol, oils; insoluble in water

Perfumer Guide

Note Position
Heart to base
Volatility
Moderate (2-6 hours)
Blending
Excellent with woods, spices
ApplicationTypical %RangeNotes
Fine Fragrance0.1-0.5%Up to 1%Powerful modifier
Body Care0.01-0.1%Up to 0.2%Sensitization concerns
Candles0.2-0.8%Up to 1.5%Heat stability
Flavor1-5 ppmUp to 10 ppmFruity applications

Classic Accords

+ Sandalwood + Vanilla = Oriental + Geranium + Patchouli = Dark Rose + Bergamot + Amber = Solar Floral

Tip: Use damascone beta to ‘lift’ heavy base notes – 0.2% can make a 10% sandalwood accord smell twice as potent.

Alternatives & Comparisons

1
Damascone Alpha CAS 43052-87-5

More green/apple-like, less tenacious. Preferred for fresh floral applications where beta might overwhelm.

2
Rosyrane Super CAS 68155-66-8

Cost-effective rose ketone with similar profile but less fruity depth. Useful for budget formulations.

3
Iso Damascone CAS 39872-57-6

More diffusive top note character, better for citrus-floral transitions.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. IFRA, REACH, EU Cosmetics Regulation standards update periodically. Consult current IFRA Standards Library before formulating. Not legal or regulatory advice.

IFRA Status

IFRA 49th Amendment restricts to 0.02% in leave-on products (Category 1) due to sensitization potential. No restrictions in rinse-off.

EU Allergen Declaration

Must be declared when present ≥0.001% in leave-on, ≥0.01% in rinse-off (Annex III of EU Cosmetics Regulation).

GHS Classification

H315 Skin irritation H317 May cause allergic skin reaction

RIFM Assessment

RIFM evaluation confirms safe use at IFRA limits. Not genotoxic or carcinogenic in available studies.

Sustainability

As a synthetic molecule, damascone beta avoids agricultural impacts of natural rose cultivation. Production typically uses petrochemical feedstocks, though some manufacturers are developing bio-based routes via fermentation. The material’s extreme potency (used at ppm levels) makes it environmentally favorable compared to natural extracts requiring large cultivation areas.

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References

  1. Bickers et al. (2003). Safety assessment of damascones. Food and Chemical Toxicology. PMID 14505838
  2. Sell C. (2006). The Chemistry of Fragrances. RSC Publishing.
  3. IFRA Standards Library IFRA 49th Amendment

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Mar 2026.

Report a data error

Physicochemical Properties

DTXSID: DTXSID90885242

Physical Properties

Molecular Weight 190.286 g/mol🔬 EPA CompTox
Density 0.946 g/cm^3🔬 EPA CTX
Boiling Point 237 °C🔬 EPA CTX
Melting Point 1.8 °C🔬 EPA CTX
Flash Point 107.25 °C🔬 EPA CTX
Refractive Index 1.491 Dimensionless📊 OPERA
Molar Volume 205.31 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 3.4 Log10 unitless🔬 EPA CTX
LogD (pH 5.5) 3.707 Log10 unitless📊 OPERA
LogD (pH 7.4) 3.707 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 6.36 Log10 unitless📊 OPERA
Water Solubility 0.001 mol/L🔬 EPA CTX
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0.023 mmHg🔬 EPA CTX
Surface Tension 30.381 dyn/cm📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 17.07 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 1 count💻 Computed
Rotatable Bonds 2 count💻 Computed
Aromatic Rings 0 count💻 Computed
Molar Refractivity 59.428 cm^3/mol📊 OPERA
Polarizability 23.559 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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