Isopulegyl acetate (CAS 57576-09-07) — Green Top Note Fragrance Ingredient

Green · Citrus

Isopulegyl acetate

CAS 57576-09-07

Origin
synthetic
Note
Top
IFRA
Generally safe
Data as of: Apr 2026

What Is Isopulegyl acetate?

Isopulegyl acetate is a synthetic fragrance ingredient used to add fresh, minty-green notes to perfumes and personal care products. You’ll encounter it in aftershaves, body sprays, and some citrus-forward fragrances. This molecule matters because it provides a crisp, uplifting character that blends well with citrus and herbal notes, helping create vibrant top notes in modern fragrances.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
No major safety concerns
Always use within recommended guidelines
CAS
57576-09-07
Formula
Mixture
MW
Variable
Odor Family
Green · Citrus
Layer 1 · Enthusiast

What Does Isopulegyl acetate Smell Like?

Isopulegyl acetate delivers a brisk, refreshing aroma reminiscent of crushed mint leaves with a subtle fruity undertone. The opening is sharply green with a cooling menthol-like effect that quickly softens into a clean herbal character. As it dries down, it reveals a faint woody-rosy nuance that provides excellent diffusion. The overall effect is like walking through a herb garden after rain – dewy, vibrant, and slightly medicinal in the best way possible.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

Isopulegyl acetate is a monoterpene ester derived from isopulegol. While not found in nature, it’s structurally related to compounds in mint and eucalyptus oils. Industrial synthesis typically involves the acetylation of isopulegol using acetic anhydride. The molecule’s stereochemistry significantly impacts its odor profile, with different isomers exhibiting varying intensity of minty-green characteristics.

Physical & Chemical Properties

Perfumer Guide

Note Position
Top
Volatility
Medium (1-2 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-3%Up to 5%Fresh top note component
Personal Care0.5-2%Up to 3%Cooling effect in aftershaves

Classic Accords

Tip: Use to brighten citrus compositions and add cooling effects to masculine fougères.

Alternatives & Comparisons

1
Menthyl acetate CAS 89-48-5

More pronounced minty-cooling effect when stronger freshness is desired.

2
Isopulegol CAS 89-79-2

Alcohol precursor with similar minty character but less diffusion.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not currently restricted by IFRA standards.

RIFM Assessment

No specific RIFM assessment found for this material.

Sustainability

As a synthetic material, isopulegyl acetate production avoids natural resource depletion. However, its synthesis requires petrochemical feedstocks and energy-intensive processes. Some manufacturers are exploring bio-based routes using renewable resources.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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