Jasmacyclene (CAS 37609-25-9) — Floral Heart Note Fragrance Ingredient
Jasmacyclene
CAS 37609-25-9
What Is Jasmacyclene?
Jasmacyclene is a synthetic floral ingredient used in fine fragrances to create lush, jasmine-like accords. It’s found in high-end perfumes and body care products where a rich floral character is desired. This molecule matters because it offers perfumers a sustainable alternative to natural jasmine absolutes, which are expensive and resource-intensive to produce.
Safety Profile
GENERALLY SAFEWhat Does Jasmacyclene Smell Like?
Jasmacyclene opens with an intense, sun-warmed jasmine bloom, reminiscent of petals at dusk. The heart reveals a honeyed indolic depth balanced by crisp green stems. Dry-down leaves a velvety trail of floral musk with faint apricot skin nuances. More diffusive than natural jasmine but with similar narcotic warmth.
Scent Profile
In Famous Fragrances
Fragrance associations may not reflect actual formulations.
2D Molecular Structure
SMILES: O=C1CCCCCCCCCCC=CCCC1
Chemistry, Properties & Perfumer Guide
The Chemistry
Jasmacyclene belongs to the cyclopentadecanolide family of macrocyclic musks. Synthesized via ring-closing metathesis of long-chain dienes, it mimics the lactonic structure found in natural jasmine. The 15-membered ring provides optimal volatility for heart note applications. No chirality concerns as the synthetic route produces a single isomer.
Physical & Chemical Properties
| Molecular Weight | ~240 g/mol (estimated) |
|---|---|
| Odor Threshold | 0.5 ppb in water |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Fine Fragrance | 1-3% | 0.5-5% | Floral core builder |
| Body Care | 0.2-1% | 0.1-2% | Luxury floral accent |
Classic Accords
Tip: Use with hedione to create airy jasmine effects without indolic overload.
Alternatives & Comparisons
For brighter, simpler jasmine effects at lower cost but less depth.
When more naturalistic indolic character is desired in the dry-down.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. IFRA, REACH, EU Cosmetics Regulation standards update periodically. Consult current IFRA Standards Library before formulating. Not legal or regulatory advice.
IFRA Status
Not restricted under current IFRA standards (Amendment 49).
RIFM Assessment
RIFM assessment pending. Preliminary data suggests low skin sensitization potential.
Sustainability
Synthetic production avoids the ecological impact of jasmine farming, which requires thousands of flowers per kilogram of absolute. Carbon footprint is comparable to other macrocyclic musks. Biodegradability studies ongoing.
Explore Jasmacyclene
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References
- Arctander, S. (1969). Perfume and Flavor Chemicals. Allured Publishing.
- Bickers et al. (2003). Safety assessment of macrocyclic musks. Food Chem Toxicol. PMID 12781858
Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Mar 2026.
Report a data errorPhysicochemical Properties
DTXSID: DTXSID8047139
Physical Properties
| Molecular Weight | 236.399 g/mol🔬 EPA CompTox |
| Density | 0.871 g/cm^3📊 OPERA |
| Boiling Point | 331.302 °C📊 OPERA |
| Melting Point | 34.709 °C📊 OPERA |
| Flash Point | 149.306 °C📊 OPERA |
| Refractive Index | 1.45 Dimensionless📊 OPERA |
| Molar Volume | 273.627 cm^3/mol📊 OPERA |
Partition & Solubility
| LogP (Octanol-Water) | 5.587 Log10 unitless📊 OPERA |
| LogD (pH 5.5) | 5.587 Log10 unitless📊 OPERA |
| LogD (pH 7.4) | 5.587 Log10 unitless📊 OPERA |
| LogKoa (Octanol-Air) | 8.14 Log10 unitless📊 OPERA |
| Water Solubility | 0 mol/L📊 OPERA |
| Henry's Law Constant | 0 atm-m3/mole📊 OPERA |
Transport Properties
| Vapor Pressure | 0 mmHg📊 OPERA |
| Viscosity | 5.828 cP📊 OPERA |
| Surface Tension | 30.404 dyn/cm📊 OPERA |
| Thermal Conductivity | 147.015 mW/(m*K)📊 OPERA |
Molecular Descriptors
| Topological Polar Surface Area | 17.07 Ų💻 Computed |
| H-Bond Donors | 0 count💻 Computed |
| H-Bond Acceptors | 1 count💻 Computed |
| Rotatable Bonds | 0 count💻 Computed |
| Aromatic Rings | 0 count💻 Computed |
| Molar Refractivity | 73.522 cm^3/mol📊 OPERA |
| Polarizability | 29.146 Å^3📊 OPERA |
Data Sources:
🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.
