Para-Cymene (CAS 99-87-6) — Citrus Heart Note Fragrance Ingredient

Para-Cymene

CAS 99-87-6

Origin
Note
IFRA
Use with awareness
Data as of: Mar 2026

What Is Para-Cymene?

Para-Cymene is a naturally occurring aromatic compound found in essential oils like cumin and thyme. People encounter it in household cleaners, air fresheners, and some perfumes. Its fresh, citrus-like scent makes it popular in products needing a clean, uplifting aroma. While generally safe, its presence in consumer products is carefully regulated due to potential skin sensitivity.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
Safe in regulated concentrations
May cause skin irritation in sensitive individuals
CAS
99-87-6
Formula
Mixture
MW
Variable
Odor Family
Layer 1 · Enthusiast

What Does Para-Cymene Smell Like?

Para-Cymene offers a bright, citrusy aroma with subtle herbaceous undertones. Imagine the zest of a freshly peeled orange blended with the crispness of crushed pine needles. Its scent evolves from an initial sharp citrus burst to a milder, woody dry-down. The overall effect is clean and invigorating, reminiscent of a sunlit Mediterranean herb garden.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Eau Sauvage(Dior, 1966)

Para-Cymene adds a crisp, citrusy lift to the top notes, enhancing the freshness of this classic cologne.

Acqua di Parma Colonia(Acqua di Parma, 1916)

Used to amplify the brightness of citrus notes, creating a vibrant opening.

Layer 2

2D Molecular Structure

p-Cymene

SMILES: CC(C)C1=CC=C(C)C=C1

Chemistry, Properties & Perfumer Guide

The Chemistry

Para-Cymene is a monoterpene, part of the cymene family. It naturally occurs in essential oils like cumin, thyme, and coriander. Industrially, it’s synthesized from turpentine or petroleum derivatives. Its structure features a benzene ring with a methyl and isopropyl group, contributing to its volatility and aroma profile.

Physical & Chemical Properties

Boiling Point177 °C
Density0.857 g/cm³

Perfumer Guide

Note Position
Top
Volatility
High (15-30 min)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-3%Up to 5%Adds citrus freshness
Household Products0.5-2%Up to 3%Clean, uplifting scent

Classic Accords

+ Lemon + Rosemary = Mediterranean + Pine + Cedar = Forest Fresh

Tip: Use sparingly to avoid overpowering other top notes.

Alternatives & Comparisons

1
Limonene CAS 138-86-3

Offers a more pronounced citrus character without the herbal undertones.

2
Terpinolene CAS 586-62-9

Provides similar freshness but with more floral complexity.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. IFRA, REACH, EU Cosmetics Regulation standards update periodically. Consult current IFRA Standards Library before formulating. Not legal or regulatory advice.

IFRA Status

No IFRA restrictions currently apply.

EU Allergen Declaration

Not listed as an EU allergen.

GHS Classification

H315 Skin irritation H319 Eye irritation

RIFM Assessment

RIFM assessment confirms safe use at current levels in consumer products.

Sustainability

Para-Cymene can be sourced sustainably from plant essential oils or synthesized from renewable turpentine. Synthetic production has a lower environmental impact than intensive farming of source plants.

Explore Para-Cymene

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References

  1. PubChem: Para-Cymene PubChem 7463
  2. IFRA Standards Library IFRA

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Mar 2026.

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Ingredient Data Sheet

CAS 99-87-6

Physical Properties

Molecular Weight134.22 g/mol🔬 PubChem
LogP (Octanol-Water)4.1🔬 PubChem
Boiling Point177.2 °C🔬 EPA CompTox
Vapor Pressure1.46 mmHg @ 25°C📊 OPERA
Flash Point47.2 °C🔬 EPA CompTox
Involatility Index0.1358💻 Calculated
log Kp (skin permeability)-0.608💻 Calculated
SMILESCC1=CC=C(C=C1)C(C)C🔬 PubChem

Volatility & Performance

Fragrance NoteTop💻 Calculated
Volatility ClassModerate💻 Calculated
Persistence Score0.5 / 5💻 Calculated

Odor & Flavor

Primary Descriptorscitrus• leffingwell
Functional Groupsaromatic💻 RDKit
“Commercial grades display a typical "gassy"-kerosene-like odor, while highly purified material smells more citrusy, reminiscent of Lemon and Bergamot topnotes, having more freshness.”📖 Arctander
p-Cymene has a strong, characteristic odor reminiscent of carrot. It tends to darken with aging.📖 Fenaroli

Flavor Notes (Arctander)

“imitation Lemon and Bergamot for perfumes and flavors. It finds some use in low-cost soap and detergent perfumes. Traces are used in Citrus and Spice flavor blends, while the concentration of para-Cymene in chewing gum may reach 250 ppm and in condiments about 125 ppm (pickles etc.).”📖 Arctander

Sensory Thresholds

Odor Detection Threshold0.6448 ppm (n=16)📖 van Gemert

Regulatory Status

FEMA NumberFEMA 2356⚖️ FEMA GRAS
GRAS StatusGenerally Recognized as Safe⚖️ FEMA GRAS
IOFI ClassificationNature Identical📖 Fenaroli
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

Physicochemical Properties

DTXSID: DTXSID3026645

Physical Properties

Molecular Weight 134.222 g/mol🔬 EPA CompTox
Density 0.855 g/cm^3🔬 EPA CTX
Boiling Point 176.914 °C🔬 EPA CTX
Melting Point -63.52 °C🔬 EPA CTX
Flash Point 47.579 °C🔬 EPA CTX
Refractive Index 1.493 Dimensionless📊 OPERA
Molar Volume 155.781 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 4.143 Log10 unitless🔬 EPA CTX
LogD (pH 5.5) 4.173 Log10 unitless📊 OPERA
LogD (pH 7.4) 4.173 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 4.31 Log10 unitless📊 OPERA
Water Solubility 0 mol/L🔬 EPA CTX
Henry's Law Constant 0.009 atm-m3/mole🔬 EPA CTX

Transport Properties

Vapor Pressure 1.724 mmHg🔬 EPA CTX
Viscosity 1.473 cP📊 OPERA
Surface Tension 28.267 dyn/cm📊 OPERA
Thermal Conductivity 123.106 mW/(m*K)📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 0 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 0 count💻 Computed
Rotatable Bonds 1 count💻 Computed
Aromatic Rings 1 count💻 Computed
Molar Refractivity 45.263 cm^3/mol📊 OPERA
Polarizability 17.944 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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