Tridecene-2-nitrile (CAS 22629-49-8) — Green Top to middle Note Fragrance Ingredient

Green · Woody

Tridecene-2-nitrile

CAS 22629-49-8

Origin
synthetic
Note
Top to middle
IFRA
Use with awareness
Data as of: Apr 2026

What Is Tridecene-2-nitrile?

Tridecene-2-nitrile is a synthetic fragrance ingredient primarily used in modern perfumery. Consumers might encounter it in niche fragrances where it contributes fresh, green, or metallic nuances. This nitrile compound matters because it offers perfumers a unique way to create crisp, modern accords that can’t be achieved with traditional materials.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
IFRA compliant at standard usage levels
Limited safety data available
CAS
22629-49-8
Formula
Mixture
MW
Variable
Odor Family
Green · Woody
Layer 1 · Enthusiast

What Does Tridecene-2-nitrile Smell Like?

Tridecene-2-nitrile presents a sharp, green character with pronounced metallic undertones, reminiscent of freshly crushed leaves or a rain-drenched greenhouse. The opening is intensely fresh, evolving into a cleaner, almost aquatic heart. Dry-down reveals subtle woody-musky facets that provide surprising tenacity for such a crisp material. Its linear profile makes it excellent for modern fragrances seeking a high-impact green note without floral sweetness.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

Tridecene-2-nitrile belongs to the nitrile class of compounds, characterized by a carbon-nitrogen triple bond. This synthetic material is produced through hydrocyanation of tridecene or related olefins. While nitriles are relatively rare in nature, they offer perfumers unique stability and odor profiles compared to aldehydes. The specific positioning of the nitrile group at the 2-position creates distinctive green-metallic characteristics.

Physical & Chemical Properties

Boiling PointNot available
DensityNot available

Perfumer Guide

Note Position
Top to middle
Volatility
Moderate (2-4 hours)
Blending
Good with citrus and woody materials
ApplicationTypical %RangeNotes
Fine Fragrance0.5-2%Up to 5%Adds crisp modernity
Functional Fragrance0.1-0.5%Up to 1%Freshness booster

Classic Accords

Tip: Use with ionones to soften the metallic edge while maintaining freshness.

Alternatives & Comparisons

1
Vernonitrile CAS 55766-79-9

Similar green profile but with more citrusy top notes and better stability in alkaline systems.

2
trans-2-Hexenenitrile CAS 5346-31-4

Shorter chain length provides more intense green character but less longevity.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No current IFRA restrictions. Listed on IFRA Transparency List.

RIFM Assessment

Not currently evaluated by RIFM. Recommended for limited use pending further safety studies.

Sustainability

As a fully synthetic material, tridecene-2-nitrile doesn’t rely on agricultural sourcing. Production typically involves petrochemical feedstocks, though newer routes may utilize bio-based precursors. Its potency means small quantities are effective, reducing overall environmental impact compared to weaker materials requiring higher doses.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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