1H-Indene, 2,3-dihydro-1,1,2,3,3-pentamethyl- (CAS 1203-17-4) — Woody Base Note Fragrance Ingredient

Woody · Balsamic

1H-Indene, 2,3-dihydro-1,1,2,3,3-pentamethyl-

CAS 1203-17-4

Origin
synthetic
Note
Base
IFRA
Use with awareness
Data as of: Apr 2026

What Is 1H-Indene, 2,3-dihydro-1,1,2,3,3-pentamethyl-?

1H-Indene, 2,3-dihydro-1,1,2,3,3-pentamethyl- is a synthetic aromatic compound used in modern perfumery to add woody and ambery nuances. It’s found in niche fragrances seeking unconventional dry-down effects. This ingredient matters as a building block for complex amber accords, providing warmth without being overly sweet or powdery like traditional amber materials.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
Not classified as hazardous
Limited toxicological data available
CAS
1203-17-4
Formula
Mixture
MW
Variable
Odor Family
Woody · Balsamic
Layer 1 · Enthusiast

What Does 1H-Indene, 2,3-dihydro-1,1,2,3,3-pentamethyl- Smell Like?

This synthetic molecule opens with a sharp, almost metallic woody character that quickly settles into a dry ambery warmth. Imagine the scent of sun-baked driftwood with a whisper of motor oil sophistication. As it evolves, it reveals a subtle leathery undertone that lingers like the memory of an old library binding. The dry-down is surprisingly smooth for such a complex structure, leaving behind a clean woody-amber signature that never becomes cloying.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

1H-Indene, 2,3-dihydro-1,1,2,3,3-pentamethyl- belongs to the indane class of synthetic aromatics. Its pentamethyl substitution pattern creates a rigid molecular framework that contributes to its excellent stability in formulations. Industrially synthesized through Friedel-Crafts alkylation reactions, this material showcases how strategic methylation can dramatically alter odor characteristics while maintaining desirable performance properties.

Physical & Chemical Properties

Perfumer Guide

Note Position
Base
Volatility
Very low (12+ hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance0.5-2%Up to 5%Amber/woody base note support
Functional Fragrance0.1-0.5%Up to 1%Background woody fixative

Classic Accords

Tip: Use with ionones to soften its metallic edge while maintaining projection.

Alternatives & Comparisons

1
Ambroxan CAS 6790-58-5

For cleaner ambery effects with better diffusion but less woody character.

2
Norlimbanol CAS 70788-30-6

When more pronounced woody dryness is desired with similar stability.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not currently restricted by IFRA standards.

RIFM Assessment

Not currently evaluated by RIFM due to limited commercial use history.

Sustainability

As a synthetic material, this compound is produced through petrochemical routes with standard industrial controls. Its potent odor profile means small quantities are required, reducing overall environmental burden compared to some natural amber materials. Future green chemistry approaches may offer more sustainable synthesis pathways.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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