2-(3,7-Dimethyl-2,6-octadienyl)cyclopentanone (CAS 68133-79-9) — Woody Heart Note Fragrance Ingredient

Woody · Floral

2-(3,7-Dimethyl-2,6-octadienyl)cyclopentanone

CAS 68133-79-9

Origin
synthetic
Note
Heart
IFRA
Use with awareness
Data as of: Apr 2026

What Is 2-(3,7-Dimethyl-2,6-octadienyl)cyclopentanone?

2-(3,7-Dimethyl-2,6-octadienyl)cyclopentanone is a synthetic fragrance compound used in perfumery for its unique olfactory properties. It is found in various fine fragrances and personal care products. This ingredient is valued for its ability to add depth and complexity to fragrance compositions, often used as a modifier to enhance other notes.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
Safe in regulated products
Potential sensitizer – use with caution
CAS
68133-79-9
Formula
Mixture
MW
Variable
Odor Family
Woody · Floral
Layer 1 · Enthusiast

What Does 2-(3,7-Dimethyl-2,6-octadienyl)cyclopentanone Smell Like?

This synthetic molecule offers a complex olfactory profile, blending woody and floral nuances with a subtle green undertone. It evolves from a fresh, slightly citrusy top note to a heart of warm, woody character, settling into a soft, musky base. The dry-down is smooth and persistent, making it a versatile ingredient in modern perfumery.

Scent Profile
Layer 2

2D Molecular Structure

Apritone

SMILES: CC(C)=CCCC(C)=CCC1CCCC1=O

Chemistry, Properties & Perfumer Guide

The Chemistry

2-(3,7-Dimethyl-2,6-octadienyl)cyclopentanone is a synthetic ketone derivative, structurally related to terpenoid compounds. It is synthesized through organic reactions involving cyclopentanone and dimethyloctadienyl precursors. The molecule features a cyclopentanone core with a dimethyloctadienyl side chain, contributing to its unique olfactory properties.

Physical & Chemical Properties

Boiling PointNot available
DensityNot available

Perfumer Guide

Note Position
Heart
Volatility
Medium (2-4 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-5%Up to 10%Used as a modifier in floral and woody accords

Classic Accords

Tip: Use in small amounts to enhance woody and floral notes without overpowering the composition.

Alternatives & Comparisons

1
Iso E Super CAS 54464-57-2

A more widely used woody amber alternative with similar blending properties.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No specific IFRA restrictions currently apply to this compound.

RIFM Assessment

No specific RIFM assessment data available for this compound.

Sustainability

As a synthetic compound, 2-(3,7-Dimethyl-2,6-octadienyl)cyclopentanone is produced in controlled laboratory environments, minimizing environmental impact compared to some natural extracts. Its synthetic origin ensures consistent quality and reduces reliance on natural resources.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Physicochemical Properties

    DTXSID: DTXSID30867486

    Physical Properties

    Molecular Weight 220.356 g/mol🔬 EPA CompTox
    Density 0.914 g/cm^3🔬 EPA CTX
    Boiling Point 298.5 °C🔬 EPA CTX
    Melting Point 23.237 °C📊 OPERA
    Flash Point 138.894 °C🔬 EPA CTX
    Refractive Index 1.486 Dimensionless📊 OPERA
    Molar Volume 241.671 cm^3/mol📊 OPERA

    Partition & Solubility

    LogP (Octanol-Water) 4.394 Log10 unitless📊 OPERA
    LogD (pH 5.5) 4.394 Log10 unitless📊 OPERA
    LogD (pH 7.4) 4.394 Log10 unitless📊 OPERA
    LogKoa (Octanol-Air) 7.44 Log10 unitless📊 OPERA
    Water Solubility 0 mol/L📊 OPERA
    Henry's Law Constant 0 atm-m3/mole📊 OPERA

    Transport Properties

    Vapor Pressure 5.899 mmHg🔬 EPA CTX
    Viscosity 5.535 cP📊 OPERA
    Surface Tension 30.476 dyn/cm📊 OPERA
    Thermal Conductivity 132.629 mW/(m*K)📊 OPERA

    Molecular Descriptors

    Topological Polar Surface Area 17.07 Ų💻 Computed
    H-Bond Donors 0 count💻 Computed
    H-Bond Acceptors 1 count💻 Computed
    Rotatable Bonds 5 count💻 Computed
    Aromatic Rings 0 count💻 Computed
    Molar Refractivity 69.38 cm^3/mol📊 OPERA
    Polarizability 27.504 Å^3📊 OPERA

    Data Sources:

    🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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