2-Cyclohexen-1-one, 3,5-diethyl-2,5-dimethyl- (CAS 39121-42-1) — Woody Middle Note Fragrance Ingredient

Woody · Spicy

2-Cyclohexen-1-one, 3,5-diethyl-2,5-dimethyl-

CAS 39121-42-1

Origin
synthetic
Note
Middle
IFRA
Generally safe
Data as of: Apr 2026

What Is 2-Cyclohexen-1-one, 3,5-diethyl-2,5-dimethyl-?

2-Cyclohexen-1-one, 3,5-diethyl-2,5-dimethyl- is a synthetic fragrance ingredient used in perfumery to add woody and spicy nuances. It is typically found in niche and artisanal fragrances. This compound contributes depth and complexity to fragrance compositions, often enhancing masculine and oriental scent profiles.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
Safe in regulated products
Use in moderation
CAS
39121-42-1
Formula
Mixture
MW
Variable
Odor Family
Woody · Spicy
Layer 1 · Enthusiast

What Does 2-Cyclohexen-1-one, 3,5-diethyl-2,5-dimethyl- Smell Like?

This molecule presents a rich, woody-spicy aroma with subtle fruity undertones. Initially, it offers a sharp, slightly camphoraceous top note that evolves into a heart of warm, resinous character. The dry-down reveals a lingering, slightly sweet woody base with hints of tobacco and leather. Its complexity makes it a versatile building block in modern perfumery.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

2-Cyclohexen-1-one, 3,5-diethyl-2,5-dimethyl- is a synthetic ketone belonging to the cyclohexenone class. It is typically synthesized through alkylation reactions of cyclohexenone derivatives. The molecule features a cyclohexenone core with ethyl and methyl substituents, contributing to its distinctive odor profile. Its synthetic origin allows for consistent quality and purity in fragrance applications.

Physical & Chemical Properties

Boiling PointN/A
DensityN/A

Perfumer Guide

Note Position
Middle
Volatility
Medium (2-4 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-3%Up to 5%Adds woody-spicy depth
Home Fragrance0.5-2%Up to 3%Enhances warm accords

Classic Accords

Tip: Use in small amounts to avoid overpowering other notes.

Alternatives & Comparisons

1
Iso E Super CAS 54464-57-2

A more widely used woody amber alternative with similar blending properties.

2
Vertofix Coeur CAS 68039-49-6

Offers a smoother woody character with less spice.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No IFRA restrictions currently apply.

RIFM Assessment

No specific RIFM assessment found.

Sustainability

As a synthetic molecule, this ingredient avoids natural resource depletion. Its production can be optimized for minimal environmental impact through green chemistry principles. The consistent quality reduces batch-to-batch variability compared to natural alternatives.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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