2-Cyclohexen-1-one, 3,5-diethyl-5,6-dimethyl- (CAS 39121-44-3) — Woody Middle Note Fragrance Ingredient

ByThe Good Scents
Woody · Balsamic

2-Cyclohexen-1-one, 3,5-diethyl-5,6-dimethyl-

CAS 39121-44-3

Origin
synthetic
Note
Middle
IFRA
Use with awareness
Data as of: Apr 2026

What Is 2-Cyclohexen-1-one, 3,5-diethyl-5,6-dimethyl-?

2-Cyclohexen-1-one, 3,5-diethyl-5,6-dimethyl- is a synthetic fragrance ingredient primarily used in perfumery. It’s found in niche fragrances and functional products like air fresheners. This molecule contributes woody-ambery nuances with subtle fruity undertones, often used to enhance depth in modern compositions.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
✓ No major restrictions reported
⚠ Limited safety data available
CAS
39121-44-3
Formula
Mixture
MW
Variable
Odor Family
Woody · Balsamic
Layer 1 · Enthusiast

What Does 2-Cyclohexen-1-one, 3,5-diethyl-5,6-dimethyl- Smell Like?

This cyclohexenone derivative presents a complex olfactory profile – opening with a crisp, slightly camphoraceous edge reminiscent of crushed pine needles. The heart reveals a surprising fruity character akin to dried apricots soaked in brandy, while the dry-down settles into a warm, ambery woodiness with whispers of tobacco leaf. Its evolution is slow and deliberate, making it valuable for extending mid-notes in compositions.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

As a substituted cyclohexenone, this molecule belongs to the cyclic enone class with two ethyl and two methyl substituents creating steric hindrance. The conjugated carbonyl system contributes to its amber-like character. Synthesized through alkylation reactions of simpler cyclohexenones, its structure prevents easy racemization, making chirality irrelevant for perfumery applications.

Physical & Chemical Properties

Perfumer Guide

Note Position
Middle
Volatility
Moderate (2-6 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance0.5-2%Up to 5%Amber-woody modifier
Functional Products0.1-0.5%Up to 1%Base note enhancer

Classic Accords

Tip: Use to bridge citrus top notes with woody bases in masculine compositions.

Alternatives & Comparisons

1
Ambroxan CAS 6790-58-5

For cleaner ambery effects with less fruity character.

2
Norlimbanol CAS 70788-30-6

When more pronounced woody dryness is desired.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No IFRA restrictions currently listed.

RIFM Assessment

No RIFM assessment publicly available.

Sustainability

As a synthetic material, production involves petrochemical feedstocks but avoids agricultural land use. Exact environmental impact depends on manufacturing processes which aren’t publicly documented for this specific molecule.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Ingredient Data Sheet

    CAS 39121-44-3
    Data Sources & Attribution
    Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

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