2-Ethylidenedecan-1-al (CAS 64825-20-3) — Green Top Note Fragrance Ingredient

Green · Citrus

2-Ethylidenedecan-1-al

CAS 64825-20-3

Origin
synthetic
Note
Top
IFRA
Use with awareness
Data as of: Apr 2026

What Is 2-Ethylidenedecan-1-al?

2-Ethylidenedecan-1-al is a synthetic fragrance ingredient used to add a modern, clean freshness to perfumes. You’ll encounter it in laundry detergents, fabric softeners, and some contemporary floral perfumes. It’s valued for its ability to enhance ‘just washed’ impressions without overpowering other notes. This aldehyde helps create sparkling top notes in fragrances, contributing to the initial burst of scent when first applied. Its subtle marine and citrus-tinged character makes it popular in aquatic and fresh compositions.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
Approved for use in consumer products
Potential skin sensitizer at high concentrations
CAS
64825-20-3
Formula
Mixture
MW
Variable
Odor Family
Green · Citrus
Layer 1 · Enthusiast

What Does 2-Ethylidenedecan-1-al Smell Like?

2-Ethylidenedecan-1-al presents a crisp, clean odor profile reminiscent of freshly laundered linens drying in sea breeze. The opening is deceptively simple – a bright, ozonic freshness with subtle citrus undertones like the zest of green mandarin. As it develops, a delicate marine aspect emerges, not fishy but rather like the mineral tang of sea spray on warm rocks. The dry-down reveals a surprisingly soft, almost powdery quality that prevents the freshness from becoming harsh. Its tenacity is moderate, making it ideal for creating transient top notes that fade gracefully into heart accords.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Cool Water(Davidoff, 1988)

Used here to amplify the aquatic freshness, contributing to that iconic ‘blue’ fragrance character. It blends with calone and citrus to create the impression of ocean mist.

Light Blue(Dolce & Gabbana, 2001)

Works in harmony with Sicilian citrus to create the sparkling, sun-drenched quality. Its marine facets enhance the fragrance’s Mediterranean beach inspiration.

L'Eau d'Issey(Issey Miyake, 1992)

Helps achieve the water droplet effect in this revolutionary aquatic floral. Its clean character prevents the lotus note from becoming too heavy.

Layer 2

2D Molecular Structure

2-Ethylidenedecan-1-al

SMILES: CCCCCCCCC(=CC)C=O

Chemistry, Properties & Perfumer Guide

The Chemistry

2-Ethylidenedecan-1-al belongs to the family of α,β-unsaturated aldehydes, characterized by a carbon-carbon double bond adjacent to the aldehyde group. This structural feature contributes to its reactivity and fresh odor profile. Industrially, it’s typically synthesized via aldol condensation reactions using decanal as a starting material. The ethylidene group at the alpha position introduces steric hindrance that affects both its odor characteristics and chemical stability. Unlike simpler aldehydes, its structure prevents rapid oxidation, giving it better shelf life in formulations while maintaining its fresh olfactory properties.

Physical & Chemical Properties

AppearanceColorless to pale yellow liquid
Boiling PointApprox. 230-240 °C (estimated)
Density~0.85 g/cm³ (estimated)
SolubilitySoluble in alcohol, insoluble in water

Perfumer Guide

Note Position
Top
Volatility
Medium (1-2 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance0.5-2%Up to 5%Fresh top note component
Functional Fragrance0.1-1%Up to 3%Laundry and cleaning products
Cosmetics0.05-0.5%Up to 1%Shampoos, body washes

Classic Accords

+ Calone + Citrus = Modern aquatic + Lily-of-the-valley + Musk = Clean floral + Bergamot + Cedar = Sporty freshness

Tip: Use in trace amounts with citrus oils to prevent the development of waxy off-notes during aging.

Alternatives & Comparisons

1
Floralozone CAS 67634-15-5

Offers similar fresh qualities but with more floral character and better stability in alkaline systems. Preferred for shampoos and soaps.

2
Melonal CAS 106-72-9

Provides a more pronounced melon-like freshness when a fruitier direction is desired in aquatic compositions.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not currently restricted by IFRA. Listed on IFRA Transparency List with no usage limitations specified.

EU Allergen Declaration

Not listed in EU allergen regulation (EC) No 1223/2009 Annex III.

GHS Classification

H315 Skin irritation H319 Eye irritation

RIFM Assessment

RIFM has reviewed safety data and established an acceptable exposure level for this material in fragrance applications.

Sustainability

As a synthetic material, 2-Ethylidenedecan-1-al production doesn’t rely on agricultural resources. Modern manufacturing processes aim to minimize solvent use and energy consumption. The material’s potency means only small quantities are needed in formulations, reducing overall environmental load compared to some natural alternatives with similar odor profiles.

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References

  1. Bauer, K. et al. (2001). Common Fragrance and Flavor Materials. Wiley-VCH. ISBN 978-3-527-30364-6
  2. IFRA Transparency List IFRA Official

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Ingredient Data Sheet

CAS 64825-20-3

Physical Properties

Molecular Weight182.3 g/mol🔬 PubChem
LogP (Octanol-Water)4.6🔬 PubChem
Boiling Point226 °C🔬 EPA CompTox
Vapor Pressure0.0191 mmHg @ 25°C📊 OPERA
Flash Point98.3 °C🔬 EPA CompTox
Involatility Index0.0015💻 Calculated
log Kp (skin permeability)-0.546💻 Calculated
SMILESCCCCCCCCC(=CC)C=O🔬 PubChem

Volatility & Performance

Fragrance NoteHeart💻 Calculated
Volatility ClassVery slow💻 Calculated
Persistence Score3.8 / 5💻 Calculated

Odor & Flavor

Primary Descriptorscitrusgreen• leffingwell
Functional Groupsaldehydealkene💻 RDKit
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

Physicochemical Properties

DTXSID: DTXSID5052331

Physical Properties

Molecular Weight 182.307 g/mol🔬 EPA CompTox
Density 0.841 g/cm^3📊 OPERA
Boiling Point 241.833 °C📊 OPERA
Melting Point 15.332 °C📊 OPERA
Flash Point 89.833 °C📊 OPERA
Refractive Index 1.444 Dimensionless📊 OPERA
Molar Volume 217.351 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 4.248 Log10 unitless📊 OPERA
LogD (pH 5.5) 4.248 Log10 unitless📊 OPERA
LogD (pH 7.4) 4.248 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 5.96 Log10 unitless📊 OPERA
Water Solubility 0 mol/L📊 OPERA
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0.018 mmHg📊 OPERA
Viscosity 2.552 cP📊 OPERA
Surface Tension 26.892 dyn/cm📊 OPERA
Thermal Conductivity 138.937 mW/(m*K)📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 17.07 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 1 count💻 Computed
Rotatable Bonds 8 count💻 Computed
Aromatic Rings 0 count💻 Computed
Molar Refractivity 57.731 cm^3/mol📊 OPERA
Polarizability 22.886 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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