2-Heptylcyclopentanone (CAS 0137-03-01) — Woody Base Note Fragrance Ingredient

Woody · Musky

2-Heptylcyclopentanone

CAS 0137-03-01

Origin
synthetic
Note
Base
IFRA
Generally safe
Data as of: Apr 2026

What Is 2-Heptylcyclopentanone?

2-Heptylcyclopentanone is a synthetic fragrance ingredient used in perfumes and scented products. It contributes a unique musky-woody character to formulations. This molecule matters because it helps create long-lasting base notes in fragrances, adding depth and complexity without being overpowering.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
No major safety concerns
Limited toxicity data available
CAS
0137-03-01
Formula
Mixture
MW
Variable
Odor Family
Woody · Musky
Layer 1 · Enthusiast

What Does 2-Heptylcyclopentanone Smell Like?

2-Heptylcyclopentanone delivers a warm, musky-woody aroma with subtle animalic undertones. The scent evolves from an initial slightly fatty, nutty character to a dry, woody base reminiscent of sandalwood and ambergris. Its tenacity makes it valuable for anchoring fragrances, providing a soft diffusion that lingers on skin for hours without becoming cloying.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

2-Heptylcyclopentanone belongs to the cyclic ketone class of fragrance compounds. It is exclusively synthetic, typically produced through cyclization reactions of appropriate aliphatic precursors. The molecule features a cyclopentanone core with a heptyl side chain, which contributes to its hydrophobic character and substantivity in fragrance applications.

Physical & Chemical Properties

Perfumer Guide

Note Position
Base
Volatility
Low (4+ hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance0.5-2%Up to 5%Base note fixative
Functional Fragrance0.1-1%Up to 3%Musky woody accent

Classic Accords

Tip: Use sparingly to enhance woody accords without overwhelming other notes.

Alternatives & Comparisons

1
Muscone CAS 541-91-3

More expensive natural musk alternative with similar substantivity but different odor profile.

2
Exaltolide CAS 106-02-5

Macrocyclic musk with cleaner odor profile for similar fixation effects.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No IFRA restrictions currently apply to 2-heptylcyclopentanone.

RIFM Assessment

Limited safety assessment available through RIFM.

Sustainability

As a synthetic material, 2-heptylcyclopentanone avoids natural resource depletion concerns. Its production can be optimized for minimal environmental impact through green chemistry approaches. The molecule’s substantivity may reduce overall fragrance load requirements in formulations.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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