2-Hexadecen-1-ol, 3,7,11,15-tetramethyl- (CAS 7541-49-3) — Floral Middle Note Fragrance Ingredient

Floral · Woody

2-Hexadecen-1-ol, 3,7,11,15-tetramethyl-

CAS 7541-49-3

Origin
synthetic
Note
Middle
IFRA
Use with awareness
Data as of: Apr 2026

What Is 2-Hexadecen-1-ol, 3,7,11,15-tetramethyl-?

2-Hexadecen-1-ol, 3,7,11,15-tetramethyl- is a synthetic fragrance ingredient primarily used in perfumery. It is encountered in fine fragrances and personal care products. This compound contributes to creating unique scent profiles, often adding depth and complexity to formulations.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
Safe in regulated products
Limited safety data available
CAS
7541-49-3
Formula
Mixture
MW
Variable
Odor Family
Floral · Woody
Layer 1 · Enthusiast

What Does 2-Hexadecen-1-ol, 3,7,11,15-tetramethyl- Smell Like?

This synthetic alcohol offers a subtle, waxy odor with faint floral undertones. It evolves slowly on the skin, starting with a clean, slightly green top note that transitions into a soft, musky heart. The dry-down reveals a delicate, almost powdery finish, making it useful for adding nuance to floral and woody compositions.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Layer 2

2D Molecular Structure

3,7,11,15-Tetramethyl-2-hexadecene-1-ol

SMILES: CC(C)CCCC(C)CCCC(C)CCCC(C)=CCO

Chemistry, Properties & Perfumer Guide

The Chemistry

2-Hexadecen-1-ol, 3,7,11,15-tetramethyl- is a branched-chain unsaturated alcohol. As a synthetic molecule, it is typically produced through controlled organic synthesis routes, often involving the reduction of corresponding aldehydes or ketones. Its structure suggests potential chirality, though specific stereochemical properties are not well-documented in fragrance literature.

Physical & Chemical Properties

Perfumer Guide

Note Position
Middle
Volatility
Medium (2-4 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-3%Up to 5%Used as a modifier

Classic Accords

Tip: Use sparingly to add subtle complexity without dominating the composition.

Alternatives & Comparisons

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No specific IFRA restrictions currently apply to this material.

RIFM Assessment

No RIFM assessment currently available for this material.

Sustainability

As a synthetic material, this compound offers consistent quality and avoids natural resource depletion. However, its environmental impact depends on the specific synthesis route and energy inputs required for production.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Physicochemical Properties

    DTXSID: DTXSID40859291

    Physical Properties

    Molecular Weight 296.539 g/mol🔬 EPA CompTox
    Density 0.798 g/cm^3📊 OPERA
    Boiling Point 352.757 °C📊 OPERA
    Melting Point 4.809 °C📊 OPERA
    Flash Point 161.782 °C📊 OPERA

    Partition & Solubility

    LogP (Octanol-Water) 6.364 dimensionless💻 Computed
    Water Solubility 0 mol/L📊 OPERA

    Transport Properties

    Vapor Pressure 0 mmHg📊 OPERA
    Viscosity 27.103 cP📊 OPERA
    Surface Tension 27.525 dyn/cm📊 OPERA
    Thermal Conductivity 142.731 mW/(m*K)📊 OPERA

    Molecular Descriptors

    Topological Polar Surface Area 20.23 Ų💻 Computed
    H-Bond Donors 1 count💻 Computed
    H-Bond Acceptors 1 count💻 Computed
    Rotatable Bonds 13 count💻 Computed
    Aromatic Rings 0 count💻 Computed
    Molar Refractivity 95.56 cm^3/mol💻 Computed

    Data Sources:

    🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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