2-Methyl-2-pentenal (CAS 623-36-9) — Green Top Note Fragrance Ingredient

Green · Sweet

2-Methyl-2-pentenal

CAS 623-36-9

Origin
synthetic
Note
Top
IFRA
Generally safe
Data as of: Apr 2026

What Is 2-Methyl-2-pentenal?

2-Methyl-2-pentenal is a synthetic fragrance ingredient used to add green, fruity, and slightly metallic nuances to perfumes. It’s often found in modern floral and fruity fragrances. This aldehyde contributes freshness and lift to top notes, making it valuable for creating vibrant, contemporary scents.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
Safe in regulated products
Potential sensitizer at high concentrations
CAS
623-36-9
Formula
Mixture
MW
Variable
Odor Family
Green · Sweet
Layer 1 · Enthusiast

What Does 2-Methyl-2-pentenal Smell Like?

2-Methyl-2-pentenal opens with a sharp, green burst reminiscent of freshly crushed leaves, evolving into a fruity character akin to underripe apples. The metallic edge adds modernity, while the dry-down reveals a subtle nuttiness. Its behavior is linear but impactful, serving as a crisp accent rather than a dominant player.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Vent Vert(Balmain, 1947)

Used to amplify the green galbanum note, creating a cutting-edge chlorophyll effect that defined mid-century freshness.

Eau Sauvage(Dior, 1966)

Provides a crisp green counterpoint to the citrus top notes, enhancing the fragrance’s modern masculinity.

Layer 2

2D Molecular Structure

2-Methylpent-2-enal

SMILES: CCC=C(C)C=O

Chemistry, Properties & Perfumer Guide

The Chemistry

2-Methyl-2-pentenal is an α,β-unsaturated aldehyde with the formula C6H10O. It’s synthesized via aldol condensation of propionaldehyde. The double bond conjugation contributes to its reactivity and distinctive odor profile. This molecule exists as E/Z isomers, with the E-isomer being more stable and prevalent in fragrance applications.

Physical & Chemical Properties

Boiling Point134-136 °C
Density0.846 g/cm³
Refractive Index1.432

Perfumer Guide

Note Position
Top
Volatility
Medium (1-2 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance0.1-0.5%Up to 1%Green accent note
Functional Fragrance0.05-0.2%Up to 0.5%Freshness booster

Classic Accords

+ Galbanum = Ultimate green + Bergamot = Modern cologne

Tip: Use sparingly to avoid overwhelming compositions with its metallic green character.

Alternatives & Comparisons

1
Hexenal CAS 66-25-1

More intensely green, less fruity. Used when a stronger leaf alcohol character is desired.

2
2-Hexenal CAS 6728-26-3

Grassier and less metallic. Preferred for naturalistic green effects.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not currently restricted by IFRA. Monitor for sensitization potential at high concentrations.

EU Allergen Declaration

Not listed as an EU allergen.

GHS Classification

H315 Skin irritation H319 Eye irritation

RIFM Assessment

RIFM has evaluated this material and found it safe at current usage levels.

Sustainability

Synthesized from petrochemical precursors. Production requires careful waste management due to aldehyde reactivity. No known natural sources, making synthetic production the only viable option for perfumery use.

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References

  1. Arctander, S. (1969). Perfume and Flavor Chemicals. Montclair, NJ.
  2. Burdock, G.A. (2010). Fenaroli’s Handbook of Flavor Ingredients. CRC Press.

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Ingredient Data Sheet

CAS 623-36-9

Physical Properties

Molecular Weight98.14 g/mol🔬 PubChem
LogP (Octanol-Water)1.4🔬 PubChem
Boiling Point138.7 °C🔬 EPA CompTox
Vapor Pressure6.0005 mmHg @ 25°C📊 OPERA
Flash Point29.5 °C🔬 EPA CompTox
Involatility Index0.6528💻 Calculated
log Kp (skin permeability)-2.305💻 Calculated
SMILESCCC=C(C)C=O🔬 PubChem

Volatility & Performance

Fragrance NoteTop💻 Calculated
Volatility ClassModerate💻 Calculated
Persistence Score0.5 / 5💻 Calculated

Odor & Flavor

Primary Descriptorsgreensweet• leffingwell
Functional Groupsaldehydealkene💻 RDKit
“Powerful and diffusive, "gassy"-green and slightly fruity odor of poor tenacity.”📖 Arctander
2-Methyl-2-pentenal has a powerful, grassy-green, slightly fruity odor.📖 Fenaroli

Flavor Notes (Arctander)

“The title aldehyde has been synthesized mainly for the purpose of using it in reconstituting the aroma in dry Coffee extracts ("Instant Coffee") and in Onion flavors. However, the material forms only a minor part of the very complex and delicate aroma-picture of Coffee.”📖 Arctander

Regulatory Status

IFRA ListedYes — see IFRA Standards for category limits⚖️ IFRA 51
IOFI ClassificationNature Identical📖 Fenaroli
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

Physicochemical Properties

DTXSID: DTXSID3052301

Physical Properties

Molecular Weight 98.145 g/mol🔬 EPA CompTox
Density 0.858 g/cm^3🔬 EPA CTX
Boiling Point 136.862 °C🔬 EPA CTX
Melting Point -94 °C🔬 EPA CTX
Flash Point 30.533 °C🔬 EPA CTX
Refractive Index 1.42 Dimensionless📊 OPERA
Molar Volume 118.311 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 1.289 Log10 unitless📊 OPERA
LogD (pH 5.5) 1.289 Log10 unitless📊 OPERA
LogD (pH 7.4) 1.289 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 3.39 Log10 unitless📊 OPERA
Water Solubility 0.116 mol/L📊 OPERA
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 7.598 mmHg🔬 EPA CTX
Viscosity 0.51 cP📊 OPERA
Surface Tension 24.305 dyn/cm📊 OPERA
Thermal Conductivity 138.347 mW/(m*K)📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 17.07 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 1 count💻 Computed
Rotatable Bonds 2 count💻 Computed
Aromatic Rings 0 count💻 Computed
Molar Refractivity 29.933 cm^3/mol📊 OPERA
Polarizability 11.867 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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