2-Pentadecanone (CAS 2345-28-0) — Musky Base Note Fragrance Ingredient
2-Pentadecanone
CAS 2345-28-0
What Is 2-Pentadecanone?
2-Pentadecanone is a synthetic musk compound used in perfumery to add depth and longevity to fragrances. It’s found in many personal care products like lotions and detergents. This ingredient matters because it helps create the warm, skin-like base notes that make fragrances last longer on your body.
Safety Profile
USE WITH AWARENESSWhat Does 2-Pentadecanone Smell Like?
2-Pentadecanone delivers a soft, musky warmth reminiscent of sun-warmed skin. Its odor profile is subtle yet persistent, blending animalic undertones with a clean, powdery dryness. Unlike sharp synthetic musks, this ketone unfolds gradually, leaving a velvety trail that enhances other base notes without overpowering them. The dry-down resembles the faint, comforting scent of well-worn cotton sheets.
Chemistry, Properties & Perfumer Guide
The Chemistry
2-Pentadecanone belongs to the aliphatic ketone class, synthesized through Friedel-Crafts acylation of long-chain fatty acids. Its 15-carbon backbone provides optimal volatility for base note applications. The ketone functional group contributes to its mild polarity, influencing both odor characteristics and solubility in common fragrance carriers.
Physical & Chemical Properties
| Boiling Point | Not available |
|---|---|
| Density | Not available |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Fine Fragrance | 0.5-2% | Up to 5% | Musky base note enhancer |
| Detergents | 0.1-0.5% | Up to 1% | Long-lasting scent retention |
Classic Accords
Tip: Use as a fixative for citrus top notes to prevent rapid evaporation.
Alternatives & Comparisons
More expensive natural musk alternative with greater diffusion but similar tenacity.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
No current IFRA restrictions.
RIFM Assessment
Under review for environmental persistence assessment.
Sustainability
As a synthetic musk, 2-Pentadecanone avoids the ethical concerns of animal-derived musks but requires petrochemical feedstocks. Recent advances in bio-catalysis may offer greener synthesis routes in future production cycles.
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