2-Phenyl-2-butenal (CAS 4411-89-6) — Floral Middle Note Fragrance Ingredient

Floral · Sweet

2-Phenyl-2-butenal

CAS 4411-89-6

Origin
synthetic
Note
Middle
IFRA
Use with awareness
Data as of: Apr 2026

What Is 2-Phenyl-2-butenal?

2-Phenyl-2-butenal is a synthetic fragrance ingredient often used to add depth to floral and fruity perfumes. It’s found in various personal care products like soaps and lotions. This molecule matters because it contributes a unique spicy, floral character that perfumers use to create complex scent profiles.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
Safe in regulated concentrations
Potential skin sensitizer
CAS
4411-89-6
Formula
Mixture
MW
Variable
Odor Family
Floral · Sweet
Layer 1 · Enthusiast

What Does 2-Phenyl-2-butenal Smell Like?

2-Phenyl-2-butenal opens with a sharp, green floralcy reminiscent of crushed geranium leaves, quickly transitioning to a honeyed, slightly spicy heart. The dry-down reveals a warm, ambery depth with a subtle leathery nuance. Its character evolves like a sun-warmed garden, starting bright and herbal before settling into a golden, resinous glow.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Chanel No. 5(Chanel, 1921)

Used sparingly to enhance the floral bouquet, adding a modern green-floral facet to the classic aldehydic structure.

Dior J'adore(Dior, 1999)

Provides a crisp, contemporary edge to the floral heart, balancing the sweetness of ylang-ylang.

Layer 2

2D Molecular Structure

Benzeneacetaldehyde, .alpha.-ethylidene-

SMILES: CC=C(C=O)C1=CC=CC=C1

Chemistry, Properties & Perfumer Guide

The Chemistry

2-Phenyl-2-butenal belongs to the α,β-unsaturated aldehyde class, known for their reactivity and distinctive odor profiles. While not found in nature, it’s synthesized through aldol condensation reactions. Its structure features both aromatic and aliphatic components, creating a bridge between floral and spicy odor characteristics.

Physical & Chemical Properties

Boiling PointNot available
DensityNot available

Perfumer Guide

Note Position
Middle
Volatility
Moderate (2-4 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance0.5-2%Up to 5%Used as floral modifier
Soaps0.1-0.5%Up to 1%Adds complexity to floral bases

Classic Accords

+ Rose + Patchouli = Modern floral + Vanilla + Tonka = Spicy oriental

Tip: Stabilize with antioxidants to prevent polymerization during storage.

Alternatives & Comparisons

1
Cinnamaldehyde CAS 104-55-2

Provides similar spicy warmth but with stronger cinnamon character and greater substantivity.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not currently restricted by IFRA standards.

RIFM Assessment

Under review by RIFM for comprehensive safety assessment.

Sustainability

As a synthetic material, production can be controlled for minimal environmental impact. No natural resources are depleted in its manufacture, though petrochemical feedstocks are typically used.

Explore 2-Phenyl-2-butenal

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References

  1. Brenna et al. (2002). Structure-Odor Relationships. Chemical Reviews. DOI: 10.1021/cr000049t

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Physicochemical Properties

DTXSID: DTXSID20863391

Physical Properties

Molecular Weight 146.189 g/mol🔬 EPA CompTox
Density 1.023 g/cm^3📊 OPERA
Boiling Point 253.574 °C📊 OPERA
Melting Point 20.236 °C📊 OPERA
Flash Point 92.496 °C📊 OPERA
Refractive Index 1.53 Dimensionless📊 OPERA
Molar Volume 147.592 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 2.132 Log10 unitless📊 OPERA
LogD (pH 5.5) 2.132 Log10 unitless📊 OPERA
LogD (pH 7.4) 2.132 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 5.21 Log10 unitless📊 OPERA
Water Solubility 0.012 mol/L📊 OPERA
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0.106 mmHg📊 OPERA
Viscosity 1.63 cP📊 OPERA
Surface Tension 35.097 dyn/cm📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 17.07 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 1 count💻 Computed
Rotatable Bonds 2 count💻 Computed
Aromatic Rings 1 count💻 Computed
Molar Refractivity 45.604 cm^3/mol📊 OPERA
Polarizability 18.079 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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