(2E,6Z)-Nona-2,6-dien-1-ol (CAS 28069-72-9) — Green Top to middle Note Fragrance Ingredient
(2E,6Z)-Nona-2,6-dien-1-ol
CAS 28069-72-9
What Is (2E,6Z)-Nona-2,6-dien-1-ol?
(2E,6Z)-Nona-2,6-dien-1-ol is a synthetic fragrance ingredient that mimics the fresh, green scent of cucumber and melon rinds. It’s often used in modern perfumes and personal care products to add a crisp, watery freshness. This molecule matters because it captures the essence of summer gardens and aquatic environments without relying on natural extracts, making fragrances more consistent and sustainable.
Safety Profile
USE WITH AWARENESSWhat Does (2E,6Z)-Nona-2,6-dien-1-ol Smell Like?
A vibrant burst of freshly cut cucumber skin with a dewy, almost metallic greenness that evolves into the pale sweetness of honeydew melon. The opening is sharply aqueous—like crushed watermelon rind with a chlorophyll bite—settling into a soft, slightly waxy vegetal heart. Dry-down reveals a whisper of damp earthiness, as if tracing the journey from garden freshness to compost.
In Famous Fragrances
Fragrance associations may not reflect actual formulations.
Used to recreate the petrichor effect of rain on vegetation, contributing an ultra-realistic wet cucumber facet that blends with ginger and cardamom.
Provides the signature watery freshness, enhancing the lotus note with its crisp melon-rind character for a transparent aquatic effect.
2D Molecular Structure
SMILES: CC\C=C/CC\C=C\CO
Chemistry, Properties & Perfumer Guide
The Chemistry
An unsaturated aliphatic alcohol with conjugated diene structure, (2E,6Z)-Nona-2,6-dien-1-ol belongs to the C9 alcohol family. Industrially synthesized via Wittig reaction or hydroformylation of hexadiene. The E,Z configuration is crucial for odor quality—isomerization diminishes the fresh character. Lacks chirality but sensitive to oxidative degradation at the double bonds, requiring antioxidant stabilization in formulations.
Physical & Chemical Properties
| Appearance | Colorless to pale yellow liquid |
|---|---|
| Boiling Point | ~210 °C (estimated) |
| Solubility | Slightly soluble in water, miscible in alcohol |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Fine Fragrance | 0.5-2% | Up to 5% | Overdosing causes metallic off-notes |
| Functional Fragrances | 0.1-0.5% | Up to 1% | Shampoos and body washes |
Classic Accords
Tip: Stabilize with 0.1% BHT to prevent oxidative degradation during aging.
Alternatives & Comparisons
For softer green effects without the cucumber sharpness—better for floral bouquets.
Natural alternative with similar green character but more earthy complexity.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
No restrictions under IFRA 51st Amendment. Recommended maximum 5% in leave-on products.
GHS Classification
RIFM Assessment
RIFM evaluation confirms safe use at current industry levels with margin of safety.
Sustainability
Synthetic production avoids agricultural land use and seasonal variability. Typically manufactured from petrochemical feedstocks, though bio-based routes via fermentation of fatty acids are under development. Lower environmental impact than natural cucumber extract which requires massive quantities of raw material.
Explore (2E,6Z)-Nona-2,6-dien-1-ol
Browse essential oils and aroma compounds.
Browse on iHerb →Affiliate disclosure: we may earn a small commission at no extra cost to you.
References
- Burdock, G.A. (2010). Fenaroli’s Handbook of Flavor Ingredients. CRC Press. ISBN 9781420090869
Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.
Report a data errorIngredient Data Sheet
CAS 28069-72-9Physical Properties
| Molecular Weight | 140.22 g/mol🔬 PubChem |
| LogP (Octanol-Water) | 2.1🔬 PubChem |
| Boiling Point | 216 °C🔬 EPA CompTox |
| Vapor Pressure | 0.0076 mmHg @ 25°C📊 OPERA |
| Flash Point | 79.9 °C🔬 EPA CompTox |
| Involatility Index | 0.0007💻 Calculated |
| log Kp (skin permeability) | -2.064💻 Calculated |
| SMILES | CCC=CCCC=CCO🔬 PubChem |
Volatility & Performance
| Fragrance Note | Heart💻 Calculated |
| Volatility Class | Very slow💻 Calculated |
| Persistence Score | 3.2 / 5💻 Calculated |
Odor & Flavor
| Primary Descriptors | cucumbergreenherbalviolet• leffingwell |
| Functional Groups | alcoholalkene💻 RDKit |
Sensory Thresholds
| Odor Detection Threshold | 0.001 ppm (n=5)📖 van Gemert |
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.
Physicochemical Properties
DTXSID: DTXSID7047192
Physical Properties
| Molecular Weight | 140.226 g/mol🔬 EPA CompTox |
| Density | 0.882 g/cm^3📊 OPERA |
| Boiling Point | 212.878 °C📊 OPERA |
| Melting Point | 12.063 °C📊 OPERA |
| Flash Point | 87.198 °C📊 OPERA |
| Refractive Index | 1.473 Dimensionless📊 OPERA |
| Molar Volume | 161.832 cm^3/mol📊 OPERA |
Partition & Solubility
| LogP (Octanol-Water) | 2.772 Log10 unitless📊 OPERA |
| LogD (pH 5.5) | 2.772 Log10 unitless📊 OPERA |
| LogD (pH 7.4) | 2.772 Log10 unitless📊 OPERA |
| LogKoa (Octanol-Air) | 6.47 Log10 unitless📊 OPERA |
| Water Solubility | 0.007 mol/L📊 OPERA |
| Henry's Law Constant | 0 atm-m3/mole📊 OPERA |
Transport Properties
| Vapor Pressure | 0.034 mmHg📊 OPERA |
| Viscosity | 3.732 cP📊 OPERA |
| Surface Tension | 28.424 dyn/cm📊 OPERA |
| Thermal Conductivity | 155.195 mW/(m*K)📊 OPERA |
Molecular Descriptors
| Topological Polar Surface Area | 20.23 Ų💻 Computed |
| H-Bond Donors | 1 count💻 Computed |
| H-Bond Acceptors | 1 count💻 Computed |
| Rotatable Bonds | 5 count💻 Computed |
| Aromatic Rings | 0 count💻 Computed |
| Molar Refractivity | 45.395 cm^3/mol📊 OPERA |
| Polarizability | 17.996 Å^3📊 OPERA |
Data Sources:
🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.
