3,12-Tridecadienenitrile (CAS 134769-33-8) — Green Middle Note Fragrance Ingredient

Green · Woody

3,12-Tridecadienenitrile

CAS 134769-33-8

Origin
synthetic
Note
Middle
IFRA
Professional use
Data as of: Apr 2026

What Is 3,12-Tridecadienenitrile?

3,12-Tridecadienenitrile is a synthetic fragrance molecule used in niche perfumery to create unique olfactory effects. It’s found in avant-garde compositions where unconventional materials are prized. This ingredient matters because it represents perfumery’s cutting edge – allowing creators to move beyond traditional scent profiles into uncharted territory.

Safety Profile

PROFESSIONAL USE
Generally safeUse with awarenessProfessional use
Limited safety data available
Professional handling recommended
CAS
134769-33-8
Formula
Mixture
MW
Variable
Odor Family
Green · Woody
Layer 1 · Enthusiast

What Does 3,12-Tridecadienenitrile Smell Like?

3,12-Tridecadienenitrile presents a sharp, metallic-green character with facets reminiscent of crushed stems and unripe citrus peel. The opening is intensely vegetal, evolving into a dry, woody-ambery base with a peculiar nutty undertone. Its dry-down leaves a persistent trail of bitter almond nuances intertwined with a rubbery, almost industrial quality that challenges conventional notions of beauty in fragrance.

Scent Profile
Layer 2

2D Molecular Structure

3,12-Tridecadienenitrile

SMILES: C=CCCCCCCCC=CCC#N

Chemistry, Properties & Perfumer Guide

The Chemistry

3,12-Tridecadienenitrile belongs to the nitrile class of compounds, characterized by a carbon-nitrogen triple bond. As a synthetic material, it’s produced through specialized organic synthesis routes involving controlled oxidation and nitrile formation. The conjugated diene structure contributes to its distinctive odor profile and reactivity. Being a synthetic molecule, it doesn’t occur naturally and is valued precisely for its unconventional olfactory properties.

Physical & Chemical Properties

Perfumer Guide

Note Position
Middle
Volatility
Medium (2-4 hours)
Blending
Challenging
ApplicationTypical %RangeNotes
Fine Fragrance0.1-0.5%Up to 1%Used sparingly for avant-garde effects
Functional FragranceNot usedN/AToo unconventional for mass-market applications

Classic Accords

Tip: Use in trace amounts to add cutting-edge modernity to green or woody compositions.

Alternatives & Comparisons

1
Violet Leaf Absolute CAS 8024-08-6

For a more natural green effect without the metallic harshness

2
Undecadienenitrile CAS 14447-25-7

Similar nitrile character but with softer fruity-green nuances

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No specific IFRA restrictions. General nitrile precautions apply.

RIFM Assessment

No RIFM assessment available due to limited commercial use.

Sustainability

As a synthetic material, 3,12-Tridecadienenitrile’s environmental impact depends on production methods. Being used in minute quantities reduces its footprint. There are no known natural alternatives with equivalent odor characteristics, making synthetic production necessary for its unique scent profile.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Ingredient Data Sheet

    CAS 134769-33-8

    Physical Properties

    Molecular Weight191.31 g/mol🔬 PubChem
    LogP (Octanol-Water)4.7🔬 PubChem
    Boiling Point266 °C🔬 EPA CompTox
    Vapor Pressure0.006 mmHg @ 25°C📊 OPERA
    Flash Point133.4 °C🔬 EPA CompTox
    Involatility Index0.0005💻 Calculated
    log Kp (skin permeability)-0.53💻 Calculated
    SMILESC=CCCCCCCCC=CCC#N🔬 PubChem

    Volatility & Performance

    Fragrance NoteHeart💻 Calculated
    Volatility ClassVery slow💻 Calculated
    Persistence Score5 / 5💻 Calculated

    Odor & Flavor

    Functional Groupsalkene💻 RDKit
    Data Sources & Attribution
    Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

    Physicochemical Properties

    DTXSID: DTXSID1073107

    Physical Properties

    Molecular Weight 191.318 g/mol🔬 EPA CompTox
    Density 0.841 g/cm^3📊 OPERA
    Boiling Point 278.256 °C📊 OPERA
    Melting Point -7.338 °C📊 OPERA
    Flash Point 130.136 °C📊 OPERA
    Refractive Index 1.463 Dimensionless📊 OPERA
    Molar Volume 225.215 cm^3/mol📊 OPERA

    Partition & Solubility

    LogP (Octanol-Water) 3.991 Log10 unitless📊 OPERA
    LogD (pH 5.5) 3.991 Log10 unitless📊 OPERA
    LogD (pH 7.4) 3.991 Log10 unitless📊 OPERA
    LogKoa (Octanol-Air) 6.9 Log10 unitless📊 OPERA
    Water Solubility 0 mol/L📊 OPERA
    Henry's Law Constant 0 atm-m3/mole📊 OPERA

    Transport Properties

    Vapor Pressure 0.003 mmHg📊 OPERA
    Viscosity 2.744 cP📊 OPERA
    Surface Tension 29.988 dyn/cm📊 OPERA
    Thermal Conductivity 158.255 mW/(m*K)📊 OPERA

    Molecular Descriptors

    Topological Polar Surface Area 23.79 Ų💻 Computed
    H-Bond Donors 0 count💻 Computed
    H-Bond Acceptors 1 count💻 Computed
    Rotatable Bonds 9 count💻 Computed
    Aromatic Rings 0 count💻 Computed
    Molar Refractivity 61.973 cm^3/mol📊 OPERA
    Polarizability 24.568 Å^3📊 OPERA

    Data Sources:

    🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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