2-Acetylthiazole (CAS 24295-03-02) — Sweet Heart Note Fragrance Ingredient
2-Acetylthiazole
CAS 24295-03-02
What Is 2-Acetylthiazole?
2-Acetylthiazole is a synthetic aroma chemical used primarily in food flavorings and some niche fragrances. It’s found in roasted, nutty, and popcorn-like scents. This ingredient matters because it provides unique savory notes that are difficult to obtain from natural sources, adding depth and complexity to modern fragrance compositions.
Safety Profile
USE WITH AWARENESSWhat Does 2-Acetylthiazole Smell Like?
2-Acetylthiazole delivers an intense, roasted character reminiscent of freshly popped popcorn with nutty undertones. Its sharp top note evolves into a warm, bready heart with hints of toasted hazelnuts. The dry-down reveals a persistent savory quality, like the crust of artisan bread. At higher concentrations, it can exhibit meaty, brothy nuances that blend well with woody and spicy accords.
Chemistry, Properties & Perfumer Guide
The Chemistry
2-Acetylthiazole belongs to the heterocyclic thiazole family, characterized by a five-membered ring containing both sulfur and nitrogen atoms. This synthetic compound is produced through various routes including the reaction of thiazole with acetyl chloride. Its structure allows for strong odor detection at extremely low concentrations due to specific receptor binding.
Physical & Chemical Properties
| Appearance | Colorless to pale yellow liquid |
|---|---|
| Odor Threshold | Extremely low (ppb range) |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Fine Fragrance | 0.1-0.5% | Up to 1% | Used sparingly for savory effects |
| Functional Fragrance | 0.05-0.2% | Up to 0.5% | Adds warmth to fabric softeners |
Classic Accords
Tip: Use in trace amounts to avoid overpowering savory effects – works best when balanced with sweet or woody notes.
Alternatives & Comparisons
Similar roasted character but with more pronounced popcorn notes and less sulfurous undertones.
Provides roasted coffee notes with less nutty character for different savory applications.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
No specific IFRA restrictions. General usage guidelines apply.
GHS Classification
RIFM Assessment
RIFM has evaluated this material with no significant concerns at typical usage levels.
Sustainability
As a synthetic material, 2-Acetylthiazole has minimal environmental impact in production. Its extreme potency means very small quantities are needed, reducing overall chemical load in formulations compared to natural alternatives with similar odor profiles.
Explore 2-Acetylthiazole
Browse essential oils and aroma compounds.
Browse on iHerb →Affiliate disclosure: we may earn a small commission at no extra cost to you.
References
- Burdock, G.A. (2010). Fenaroli’s Handbook of Flavor Ingredients. CRC Press.
- Arctander, S. (1969). Perfume and Flavor Chemicals. Allured Publishing.
Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.
Report a data error
