3-Methyl-1-pentanol (CAS 589-35-5) — Green Top to middle Note Fragrance Ingredient

Green · Sweet

3-Methyl-1-pentanol

CAS 589-35-5

Origin
synthetic
Note
Top to middle
IFRA
Generally safe
Data as of: Apr 2026

What Is 3-Methyl-1-pentanol?

3-Methyl-1-pentanol is a synthetic alcohol used in fragrances to add fruity, green, and slightly woody nuances. You might encounter it in fresh floral compositions or fruity body care products. This ingredient matters because it helps create natural-smelling fruit accords without using actual fruit extracts, which are often unstable in formulations.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
No major restrictions
Moderate skin sensitivity potential
CAS
589-35-5
Formula
Mixture
MW
Variable
Odor Family
Green · Sweet
Layer 1 · Enthusiast

What Does 3-Methyl-1-pentanol Smell Like?

3-Methyl-1-pentanol presents a complex olfactory profile that evolves intriguingly. The initial burst suggests unripe bananas mingled with green apple skins – tart, slightly astringent, with a waxy undertone. As it settles, the character softens into a melon-like sweetness with whispers of freshly cut grass. The dry-down reveals subtle woody facets reminiscent of young twigs, making it surprisingly versatile. In dilution, it acquires an almost floral delicacy that belies its alcoholic nature.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Eau Dynamisante(Clarins, 1987)

Used here to enhance the crisp green apple top notes while providing naturalistic fruity depth that lasts through the heart phase.

Un Jardin sur le Nil(Hermès, 2005)

Contributes to the tart mango accord, blending seamlessly with hedione to create the illusion of sun-warmed fruit skins.

Layer 2

2D Molecular Structure

3-Methyl-1-pentanol

SMILES: CCC(C)CCO

Chemistry, Properties & Perfumer Guide

The Chemistry

3-Methyl-1-pentanol belongs to the aliphatic alcohol class, specifically a branched-chain hexanol isomer. While theoretically possible in nature, it’s predominantly synthesized via hydroformylation of 2-methyl-1-butene followed by hydrogenation. The molecule exhibits chirality – the (R)-enantiomer tends to smell fruitier while the (S)-form leans greener. Industrial production typically yields racemic mixtures unless specific catalysts are employed.

Physical & Chemical Properties

Boiling Point148-150 °C
Density0.82 g/cm³
Refractive Index1.417

Perfumer Guide

Note Position
Top to middle
Volatility
Medium (1-3 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance0.5-2%Up to 5%Fruity-green modifier
Body Care0.1-0.5%Up to 1%Freshness booster

Classic Accords

+ Galbanum + Hexyl Acetate = Tropical Fruit + Cis-3-Hexenol + Calone = Dewy Green

Tip: Use with citrus terpenes to prevent harsh alcoholic notes from dominating the top.

Alternatives & Comparisons

1
1-Hexanol CAS 111-27-3

More straightforward green-alcoholic character when less fruity complexity is desired.

2
3-Methyl-2-buten-1-ol CAS 556-82-1

For brighter, more pungent green notes with less fruity undertone.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not currently restricted under any IFRA standards.

GHS Classification

H315 Skin irritation H319 Eye irritation

RIFM Assessment

RIFM assessment confirms safe use at current industry levels with no sensitization concerns.

Sustainability

As a synthetic material, 3-methyl-1-pentanol has minimal environmental impact in production compared to natural extracts. Its efficient synthesis from petrochemical feedstocks makes it carbon-footprint favorable versus fruit-derived alternatives requiring agricultural land use.

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References

  1. Burdock, G.A. (2010). Fenaroli’s Handbook of Flavor Ingredients. CRC Press. ISBN 9781420090860

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Physicochemical Properties

DTXSID: DTXSID20862248

Physical Properties

Molecular Weight 102.177 g/mol🔬 EPA CompTox
Density 0.823 g/cm^3🔬 EPA CTX
Boiling Point 151.5 °C🔬 EPA CTX
Melting Point -26.676 °C📊 OPERA
Flash Point 58.05 °C🔬 EPA CTX
Refractive Index 1.414 Dimensionless📊 OPERA
Molar Volume 125.459 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 1.748 Log10 unitless📊 OPERA
LogD (pH 5.5) 1.748 Log10 unitless📊 OPERA
LogD (pH 7.4) 1.748 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 4.37 Log10 unitless📊 OPERA
Water Solubility 0.084 mol/L🔬 EPA CTX
Henry's Law Constant 0 atm-m3/mole🔬 EPA CTX

Transport Properties

Vapor Pressure 1.768 mmHg📊 OPERA
Viscosity 3.13 cP📊 OPERA
Surface Tension 25.866 dyn/cm📊 OPERA
Thermal Conductivity 143.893 mW/(m*K)📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 20.23 Ų💻 Computed
H-Bond Donors 1 count💻 Computed
H-Bond Acceptors 1 count💻 Computed
Rotatable Bonds 3 count💻 Computed
Aromatic Rings 0 count💻 Computed
Molar Refractivity 31.34 cm^3/mol📊 OPERA
Polarizability 12.424 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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