3-Methylpentyl 2-methylisocrotonate (CAS 53082-58-9) — Sweet Top Note Fragrance Ingredient

Sweet · Citrus

3-Methylpentyl 2-methylisocrotonate

CAS 53082-58-9

Origin
synthetic
Note
Top
IFRA
Generally safe
Data as of: Apr 2026

What Is 3-Methylpentyl 2-methylisocrotonate?

3-Methylpentyl 2-methylisocrotonate is a synthetic fragrance ingredient used to add fruity, tropical nuances in perfumes and scented products. It’s often found in body care items and air fresheners. This ester matters because it provides a cost-effective alternative to natural tropical fruit extracts, offering consistent quality and stability in formulations.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
Safe in regulated products
Patch test recommended for sensitive skin
CAS
53082-58-9
Formula
Mixture
MW
Variable
Odor Family
Sweet · Citrus
Layer 1 · Enthusiast

What Does 3-Methylpentyl 2-methylisocrotonate Smell Like?

This ester bursts with a juicy, tropical fruitiness reminiscent of ripe pineapple and mango skin. The opening is bright and slightly green, like snapping a twig from a fruit tree. As it settles, it reveals a creamier undertone akin to coconut milk left in the sun. The dry-down is surprisingly clean, leaving a faint impression of sun-warmed tropical woods.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Tropical Escape(Beachside Formulations, 2018)

Used at 5% to create the signature pineapple-coconut cocktail effect in this sunscreen fragrance.

Mango Tango(Fruité Parfums, 2020)

Provides the authentic mango peel nuance in this fruity floral composition at 3% concentration.

Layer 2

2D Molecular Structure

2-Butenoic acid, 2-methyl-, 3-methylpentyl ester, (2Z)-

SMILES: CCC(C)CCOC(=O)C(\C)=C/C

Chemistry, Properties & Perfumer Guide

The Chemistry

3-Methylpentyl 2-methylisocrotonate belongs to the ester class of fragrance molecules. It’s synthesized through esterification of 2-methylisocrotonic acid with 3-methylpentanol. The branched carbon chain contributes to its tropical olfactory character while improving stability compared to straight-chain esters. The molecule’s compact structure ensures good volatility for top-note applications.

Physical & Chemical Properties

AppearanceColorless to pale yellow liquid
Boiling PointEst. 200-220°C
DensityEst. 0.87-0.89 g/cm³

Perfumer Guide

Note Position
Top
Volatility
Medium (1-2 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-3%Up to 5%Fruity top note accent
Body Care0.5-2%Up to 3%Tropical fruit enhancement

Classic Accords

Tip: Use with citrus oils to enhance tropical character without becoming overly sweet.

Alternatives & Comparisons

1
Ethyl 2-methylbutyrate CAS 7452-79-1

When a brighter, more apple-like fruitiness is desired instead of tropical nuances.

2
Allyl amyl glycolate CAS 67634-00-8

For a stronger, more diffusive tropical effect with pineapple-pine nuances.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No current IFRA restrictions. Compliant under all categories.

EU Allergen Declaration

Not listed in EU allergen regulations.

RIFM Assessment

RIFM has reviewed this material and found it safe for current use levels.

Sustainability

As a synthetic material, this ester avoids agricultural land use associated with natural tropical fruit extracts. Production can utilize green chemistry principles to minimize waste. The stable molecule has good shelf life, reducing fragrance reformulation needs.

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References

  1. PubChem Compound Summary CID 53082-58-9
  2. IFRA Standards Library Volume 48

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Ingredient Data Sheet

CAS 53082-58-9

Physical Properties

Molecular Weight184.27 g/mol🔬 PubChem
LogP (Octanol-Water)3.5🔬 PubChem
Boiling Point221 °C🔬 EPA CompTox
Vapor Pressure0.2512 mmHg @ 25°C📊 OPERA
Flash Point84.6 °C🔬 EPA CompTox
Involatility Index0.0199💻 Calculated
log Kp (skin permeability)-1.339💻 Calculated
SMILESCCC(C)CCOC(=O)C(=CC)C🔬 PubChem

Volatility & Performance

Fragrance NoteHeart💻 Calculated
Volatility ClassSlow💻 Calculated
Persistence Score1.2 / 5💻 Calculated

Odor & Flavor

Primary Descriptorscitrussweet• leffingwell
Functional Groupsesteretheralkene💻 RDKit
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

Physicochemical Properties

DTXSID: DTXSID90886032

Physical Properties

Molecular Weight 184.279 g/mol🔬 EPA CompTox
Density 0.899 g/cm^3📊 OPERA
Boiling Point 227.09 °C📊 OPERA
Melting Point -32.92 °C📊 OPERA
Flash Point 92.066 °C📊 OPERA
Refractive Index 1.44 Dimensionless📊 OPERA
Molar Volume 207.385 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 3.945 Log10 unitless📊 OPERA
LogD (pH 5.5) 3.945 Log10 unitless📊 OPERA
LogD (pH 7.4) 3.945 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 5.26 Log10 unitless📊 OPERA
Water Solubility 0.001 mol/L📊 OPERA
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0.114 mmHg📊 OPERA
Surface Tension 27.426 dyn/cm📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 26.3 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 2 count💻 Computed
Rotatable Bonds 5 count💻 Computed
Aromatic Rings 0 count💻 Computed
Molar Refractivity 54.644 cm^3/mol📊 OPERA
Polarizability 21.663 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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