5-Benzofuranol, 3-methyl- (CAS 7182-21-0) — Woody Heart to base Note Fragrance Ingredient
5-Benzofuranol, 3-methyl-
CAS 7182-21-0
What Is 5-Benzofuranol, 3-methyl-?
5-Benzofuranol, 3-methyl- is a synthetic fragrance compound used in modern perfumery to add distinctive woody and balsamic nuances. It’s found in niche fragrances and candle formulations. This ingredient matters because it provides perfumers with a unique building block for creating unconventional scent profiles, often adding depth to woody or amber accords where traditional materials might be too heavy.
Safety Profile
USE WITH AWARENESSWhat Does 5-Benzofuranol, 3-methyl- Smell Like?
3-Methyl-5-benzofuranol presents a fascinating duality – opening with a subtle medicinal sharpness that quickly mellows into a warm, resinous character reminiscent of aged parchment and antique wooden chests. The dry-down reveals a delicate balance between dry woody facets and a whisper of vanillic sweetness, behaving like a lighter cousin to cashmeran with better diffusion. Its tenacity is moderate, clinging to skin for 4-6 hours while gradually softening into a skin-scent muskiness.
In Famous Fragrances
Fragrance associations may not reflect actual formulations.
Used as a core component to create an enigmatic woody-amber skeleton, providing structure without heaviness. Its synthetic purity allows precise modulation of the fragrance’s diffusion pattern.
Employed in the heart accord to bridge fiery spices and smoky woods, lending a smooth balsamic undertone that prevents the composition from becoming too acrid.
Chemistry, Properties & Perfumer Guide
The Chemistry
3-Methyl-5-benzofuranol belongs to the benzofuran class of aromatic compounds, characterized by fused benzene and furan rings. While not found in nature, its structural analogs occur in some plant resins. Industrial synthesis typically proceeds through Friedel-Crafts alkylation of benzofuran precursors, followed by selective oxidation. The methyl group at position 3 creates steric hindrance that influences both its odor characteristics and chemical reactivity, making it more stable than unsubstituted benzofuranols.
Physical & Chemical Properties
| Appearance | Colorless to pale yellow crystals |
|---|---|
| Molecular Weight | 148.17 g/mol |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Fine Fragrance | 0.5-2% | Up to 5% | Used as woody-balsamic modifier |
| Home Fragrance | 1-3% | Up to 8% | Provides warmth in candle formulations |
Classic Accords
Tip: Use with ionones to create intriguing wood-floral hybrids with excellent diffusion.
Alternatives & Comparisons
For more pronounced musky-woody effects with greater tenacity, though lacks the balsamic subtlety of 3-methyl-5-benzofuranol.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
Not currently restricted by IFRA standards. Classified as a synthetic ingredient without specific usage limits.
RIFM Assessment
Under review by RIFM as part of ongoing synthetic materials safety assessment program.
Sustainability
As a synthetic material, 3-methyl-5-benzofuranol offers advantages in consistency and reduces pressure on natural resources. Production typically uses petrochemical feedstocks, though green chemistry approaches are being explored for similar benzofuran derivatives. Its high potency means small quantities are effective, reducing overall environmental load.
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