Acetic acid, anhydride, reaction products with (1S,3aR,4S,8aS)-decahydro-4,8,8-trimethyl-9-methylene-1,4-methanoazulene (CAS 71549-77-4) — Woody Middle Note Fragrance Ingredient

Woody · Balsamic

Acetic acid, anhydride, reaction products with (1S,3aR,4S,8aS)-decahydro-4,8,8-trimethyl-9-methylene-1,4-methanoazulene

CAS 71549-77-4

Origin
synthetic
Note
Middle
IFRA
Use with awareness
Data as of: Apr 2026

What Is Acetic acid, anhydride, reaction products with (1S,3aR,4S,8aS)-decahydro-4,8,8-trimethyl-9-methylene-1,4-methanoazulene?

This synthetic compound is a specialized fragrance ingredient derived from acetic acid and a complex terpene structure. It’s used in niche perfumery to create unique woody-amber effects. While not commonly encountered in everyday products, it offers perfumers a sophisticated tool for crafting distinctive accords.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
Limited safety data available
Potential skin sensitizer
CAS
71549-77-4
Formula
Mixture
MW
Variable
Odor Family
Woody · Balsamic
Layer 1 · Enthusiast

What Does Acetic acid, anhydride, reaction products with (1S,3aR,4S,8aS)-decahydro-4,8,8-trimethyl-9-methylene-1,4-methanoazulene Smell Like?

The scent profile presents an intriguing duality – sharp acetic top notes quickly give way to a deep, resinous heart reminiscent of aged woods and fossilized amber. The dry-down reveals a complex interplay between chemical precision and natural warmth, with subtle camphoraceous undertones that linger close to the skin.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

This compound results from the reaction of acetic anhydride with a modified decahydroazulene structure, creating an ester-like derivative. The synthesis involves careful control of reaction conditions to preserve the stereochemistry of the terpene core. The product exhibits both the reactivity of acetic derivatives and the stability of fused ring systems.

Physical & Chemical Properties

AppearanceClear viscous liquid
SolubilitySoluble in alcohol

Perfumer Guide

Note Position
Middle
Volatility
Medium (2-4 hours)
Blending
Moderate
ApplicationTypical %RangeNotes
Fine Fragrance0.5-2%Up to 5%Used as woody-amber modifier
Functional Fragrance0.1-0.5%Up to 1%Limited use due to potency

Classic Accords

Tip: Use sparingly in woody bases to add depth without overwhelming other notes.

Alternatives & Comparisons

1
Ambroxan CAS 6790-58-5

More widely available amber alternative with similar longevity but less chemical character.

2
Cedramber CAS 469-61-4

Woody-amber material with better safety profile and more predictable performance.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No specific IFRA restrictions. General guidelines for acetic acid derivatives apply.

GHS Classification

H315 Skin irritation

RIFM Assessment

Not currently evaluated by RIFM. Use with caution pending further safety data.

Sustainability

As a fully synthetic material, production avoids natural resource depletion. However, the multi-step synthesis requires careful solvent management and energy input. Future green chemistry approaches may improve the environmental profile.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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