Allyl (cyclohexyloxy)acetate (CAS 68901-15-5) — Green Top Note Fragrance Ingredient

Green · Citrus

Allyl (cyclohexyloxy)acetate

CAS 68901-15-5

Origin
synthetic
Note
Top
IFRA
Use with awareness
Data as of: Apr 2026

What Is Allyl (cyclohexyloxy)acetate?

Allyl (cyclohexyloxy)acetate is a synthetic fragrance ingredient used in modern perfumery to create fresh, green, and slightly fruity accords. You might encounter it in body sprays, fabric conditioners, and some contemporary citrus colognes. This molecule matters because it helps perfumers build crisp top notes that transition smoothly into floral or woody heart notes, offering a versatile building block for fresh fragrance compositions.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
IFRA compliant at standard usage levels
Potential skin sensitizer at high concentrations
CAS
68901-15-5
Formula
Mixture
MW
Variable
Odor Family
Green · Citrus
Layer 1 · Enthusiast

What Does Allyl (cyclohexyloxy)acetate Smell Like?

Allyl (cyclohexyloxy)acetate opens with a burst of crisp green apple peel and unripe pear, underscored by a subtle metallic freshness reminiscent of rain on hot pavement. As it evolves, the scent reveals a delicate floralcy akin to lily-of-the-valley stems, with a clean soapy undertone that prevents sweetness from dominating. The dry-down is surprisingly persistent for a top note, leaving a whisper of wet moss and crushed galbanum leaves. When overdosed, it can develop a harsh, plastic-like edge that requires careful balancing with citrus or woody notes.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Eau Dynamisante(Clarins, 1987)

Used here to amplify the invigorating citrus-green character, providing longevity to the initial freshness while allowing the herbal heart notes to emerge smoothly.

Jean-Claude Ellena employed this molecule to recreate the petrichor effect of rain on dry earth, blending its wet green facets with melon and ginger notes.

Layer 2

2D Molecular Structure

2-Propen-1-yl 2-(cyclohexyloxy)acetate

SMILES: C=CCOC(=O)COC1CCCCC1

Chemistry, Properties & Perfumer Guide

The Chemistry

Allyl (cyclohexyloxy)acetate belongs to the ester class, synthesized through esterification of cyclohexanol with allyl chloroacetate. The molecule features both an allyl group (providing reactivity) and a cyclohexyl ether moiety (contributing to its fresh-green odor profile). While purely synthetic in commerce, its structure bears resemblance to certain naturally occurring green odorants found in galbanum and violet leaf. The acetate group lends volatility, making it particularly useful as a top note modifier.

Physical & Chemical Properties

AppearanceColorless to pale yellow liquid
Boiling Point~210 °C (estimated)
Density~0.95 g/cm³ (estimated)

Perfumer Guide

Note Position
Top
Volatility
Medium-high (30-90 min)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance0.5-2%Up to 5%Fresh top note component
Functional Fragrance1-3%Up to 8%Green-modifier in detergents

Classic Accords

Tip: Stabilize with antioxidants to prevent discoloration in alcohol-based perfumes.

Alternatives & Comparisons

1
Verdox CAS 88-41-5

When a more diffusive green-woody character is needed without the fruity facets.

2
Stemone CAS 63801-99-6

For a sharper green effect with better persistence in the heart phase.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No current IFRA restrictions (as of Amendment 49).

GHS Classification

H315 Skin irritation H319 Eye irritation

RIFM Assessment

RIFM evaluation ongoing; preliminary data suggests safe use below 5% in leave-on products.

Sustainability

As a synthetic material, Allyl (cyclohexyloxy)acetate has minimal environmental impact during production compared to natural alternatives. Its synthesis avoids agricultural land use and seasonal variability. However, the petrochemical origin raises carbon footprint considerations that some brands may wish to offset.

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References

  1. Bauer et al. (2001). Modern Synthetic Methods in Fragrance Chemistry. Chemistry & Biodiversity. DOI:10.1002/cbdv.200100001

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Physicochemical Properties

DTXSID: DTXSID1071824

Physical Properties

Molecular Weight 198.262 g/mol🔬 EPA CompTox
Density 1.017 g/cm^3🔬 EPA CTX
Boiling Point 254.838 °C📊 OPERA
Melting Point -60 °C🔬 EPA CTX
Flash Point 123 °C🔬 EPA CTX
Refractive Index 1.462 Dimensionless📊 OPERA
Molar Volume 197.266 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 1.92 Log10 unitless🔬 EPA CTX
LogD (pH 5.5) 2.382 Log10 unitless📊 OPERA
LogD (pH 7.4) 2.382 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 5.8 Log10 unitless📊 OPERA
Water Solubility 0.008 mol/L📊 OPERA
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0.298 mmHg🔬 EPA CTX
Viscosity 4.348 cP📊 OPERA
Surface Tension 32.519 dyn/cm📊 OPERA
Thermal Conductivity 143.012 mW/(m*K)📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 35.53 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 3 count💻 Computed
Rotatable Bonds 5 count💻 Computed
Aromatic Rings 0 count💻 Computed
Molar Refractivity 54.279 cm^3/mol📊 OPERA
Polarizability 21.518 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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