Cashmeran (CAS 33704-61-9) — Musky Heart Note Fragrance Ingredient

Cashmeran

CAS 33704-61-9

Origin
Note
IFRA
Generally safe
Data as of: Mar 2026

What Is Cashmeran?

Cashmeran is a modern synthetic musk used in luxury perfumes and fabric softeners. It creates a warm, velvety scent reminiscent of cashmere wool. This ingredient matters because it provides long-lasting softness to fragrances without using animal-derived musks, making it both luxurious and cruelty-free.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
IFRA approved for use
Potential skin sensitizer at high concentrations
CAS
33704-61-9
Formula
Mixture
MW
Variable
Odor Family
Layer 1 · Enthusiast

What Does Cashmeran Smell Like?

Cashmeran unfolds like a luxurious textile – initially crisp with a peppery sparkle that quickly softens into warm suede and wood tones. The heart reveals a plush, musky character with subtle ambery undertones, while the dry-down lingers as a skin-like musk with whispers of cedar and vanilla. Unlike animalic musks, it maintains an airy softness throughout its evolution, like cashmere fibers catching light.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Dior Homme(Dior, 2005)

Used as a modern musk alternative to create the fragrance’s signature suede-like texture, blending with iris and cocoa for a contemporary masculine elegance.

Molecule 04(Escentric Molecules, 2010)

Showcases Cashmeran solo to demonstrate its full spectrum from peppery top notes to velvety dry-down, creating a ‘your skin but better’ effect.

Black Orchid(Tom Ford, 2006)

Provides warmth and diffusion to the dark floral composition, acting as a bridge between the patchouli base and truffle accord.

La Vie Est Belle(Lancôme, 2012)

Contributes softness to the gourmand structure, rounding out the sharpness of patchouli with its textile-like musk character.

Santal 33(Le Labo, 2011)

Used to amplify the wood notes while adding a skin-scent dimension that makes the fragrance more wearable.

Layer 2

2D Molecular Structure

Cashmeran

SMILES: CC1C(C)(C)C2=C(C(=O)CCC2)C1(C)C

Chemistry, Properties & Perfumer Guide

The Chemistry

Cashmeran belongs to the indane chemical class, specifically a trimethylindane derivative. While not found in nature, its structure mimics certain woody-musky compounds from natural sources. Industrial synthesis typically begins with petrochemical precursors through Friedel-Crafts alkylation reactions. The molecule’s rigid indane framework contributes to its stability and longevity in formulations. Unlike traditional musks, it lacks the polycyclic structure that causes environmental persistence issues.

Physical & Chemical Properties

Boiling Point285 °C
Density0.98 g/cm³
Flash Point>100 °C
Vapor Pressure0.001 mmHg at 25°C
SolubilityInsoluble in water, soluble in alcohol

Perfumer Guide

Note Position
Base
Volatility
Low (6+ hours)
Blending
Excellent
ApplicationTypical %RangeNotes
Fine Fragrance1-3%0.5-5%Provides musky warmth
Detergents0.1-0.5%Up to 1%Fabric-softening effect
Candles2-4%1-6%Enhances throw
Body Care0.5-1.5%Up to 2%Skin-scent effect

Classic Accords

+ Ambroxan + Vanilla = Modern Musk + Patchouli + Bergamot = Contemporary Chypre + Iso E Super + Cedar = Textured Wood

Tip: Use below 5% to avoid overwhelming other notes; excels when paired with ionones for softness.

Alternatives & Comparisons

1
Ethylene Brassylate CAS 105-95-3

A macrocyclic musk with similar softness but more floral character; preferred when needing greater diffusion.

2
Galaxolide CAS 1222-05-5

Stronger traditional musk for formulations requiring more projection and less woody character.

3
Velvione CAS 37609-25-9

More animalic musk alternative when seeking greater sensuality in the dry-down.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. IFRA, REACH, EU Cosmetics Regulation standards update periodically. Consult current IFRA Standards Library before formulating. Not legal or regulatory advice.

IFRA Status

No IFRA restrictions; approved for all categories under Amendment 49.

RIFM Assessment

Evaluated by RIFM in 2015 with no significant safety concerns at current usage levels.

Sustainability

As a synthetic material, Cashmeran avoids the ecological issues of natural musk harvesting. Its production doesn’t require endangered species or extensive land use. The molecule’s relatively simple structure makes it more biodegradable than traditional polycyclic musks, though proper wastewater treatment is still recommended during manufacturing.

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References

  1. Bauer et al. (2001). Synthetic Musks in Fragrances. Chemistry & Biodiversity. DOI:10.1002/cbdv.200400001
  2. IFRA Standards Library (2023). Amendment 49. IFRA Standards
  3. RIFM Monograph (2015). Cashmeran Safety Assessment. RIFM Database

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Mar 2026.

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Physicochemical Properties

DTXSID: DTXSID8047399

Physical Properties

Molecular Weight 206.329 g/mol🔬 EPA CompTox
Density 0.969 g/cm^3🔬 EPA CTX
Boiling Point 256 °C🔬 EPA CTX
Melting Point 33 °C🔬 EPA CTX
Flash Point 117 °C🔬 EPA CTX
Refractive Index 1.495 Dimensionless📊 OPERA
Molar Volume 213.66 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 4.2 Log10 unitless🔬 EPA CTX
LogD (pH 5.5) 3.956 Log10 unitless📊 OPERA
LogD (pH 7.4) 3.956 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 6.36 Log10 unitless📊 OPERA
Water Solubility 0 mol/L🔬 EPA CTX
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0.035 mmHg🔬 EPA CTX
Surface Tension 33.47 dyn/cm📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 17.07 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 1 count💻 Computed
Rotatable Bonds 0 count💻 Computed
Aromatic Rings 0 count💻 Computed
Molar Refractivity 62.341 cm^3/mol📊 OPERA
Polarizability 24.714 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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