Cedrol (CAS 77-53-2) — Woody Base Note Fragrance Ingredient




Cedrol

CAS 77-53-2

Origin
Note
IFRA
Generally safe
Data as of: Mar 2026

What Is Cedrol?

Cedrol is a naturally occurring alcohol found in cedarwood oil, giving it that distinctive woody aroma. You’ll encounter it in men’s colognes, home fragrances, and natural insect repellents. As a key component of cedar’s scent profile, cedrol provides longevity and depth to woody accords, making it invaluable for creating forest-like or pencil-shaving freshness in perfumery.

Safety Profile

GENERALLY SAFE

Generally safeUse with awarenessProfessional use
No known restrictions
Potential skin sensitivity at high concentrations
CAS
77-53-2
Formula
Mixture
MW
Variable
Odor Family
Layer 1 · Enthusiast

What Does Cedrol Smell Like?

Cedrol opens with a sharp, pencil-like woodiness reminiscent of freshly sharpened cedar pencils. As it evolves, the scent becomes creamier, revealing subtle camphoraceous undertones and a clean, almost laundry-like dryness. The dry-down is remarkably persistent – like the lingering scent of a well-used cedar chest, blending warm wood resins with a faintly medicinal edge that prevents it from becoming overly sweet.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Terre d’Hermès(Hermès, 2006)

Cedrol contributes to the flinty mineral accord that makes this modern classic smell like wet stones and fresh-cut cedar.

Encre Noire(Lalique, 2006)

Here cedrol amplifies the ink-like vetiver, creating a stark woody profile reminiscent of charred cedar planks.

Layer 2

2D Molecular Structure

(+)-Cedrol

SMILES: [H][C@@]12CC[C@@H](C)[C@]11C[C@]([H])(C2(C)C)[C@](C)(O)CC1

Chemistry, Properties & Perfumer Guide

The Chemistry

Cedrol is a sesquiterpene alcohol with the molecular formula C15H26O. It occurs naturally in several Juniperus and Cupressus species. Industrially, it’s typically isolated from Texas cedarwood oil via fractional distillation. The molecule has three chiral centers, with the (+)-enantiomer being more common in nature and possessing a stronger odor profile. Commercial production sometimes involves hydrogenation of cedrene derivatives.

Physical & Chemical Properties

Boiling Point 291-294 °C
Melting Point 86-87 °C
Density 0.98 g/cm³

Perfumer Guide

Note Position
Base
Volatility
Very low (days)
Blending
Good with woods, spices
Application Typical % Range Notes
Fine Fragrance 1-3% Up to 5% Adds woody depth
Home Fragrance 2-5% Up to 10% Long-lasting wood note

Classic Accords

+ Vetiver + Patchouli = Dark Woods
+ Amber + Vanilla = Oriental

Tip: Use cedrol to anchor citrus top notes in woody compositions.

Alternatives & Comparisons

1
Cedryl acetate CAS 77-54-3

More diffusive with a fruity nuance, used when a lighter cedar effect is desired.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. IFRA, REACH, EU Cosmetics Regulation standards update periodically. Consult current IFRA Standards Library before formulating. Not legal or regulatory advice.

IFRA Status

Not restricted by IFRA

RIFM Assessment

RIFM assessment confirms safe use at current levels.

Sustainability

Most commercial cedrol comes from sustainable Texas cedarwood oil distillation. Synthetic production exists but is less common due to the complexity of the molecule. Cedar forests are generally fast-growing and managed as renewable resources.

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Industry & Science Data

Odor Detection Threshold
200 ppb
in air (orthonasal)
Ref: van Gemert, Odour Thresholds (2011)
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References

  1. Burdock, G.A. (2010). Fenaroli’s Handbook of Flavor Ingredients. CRC Press.
  2. PubChem CID 65575 PubChem

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Mar 2026.

Report a data error

Physicochemical Properties

DTXSID: DTXSID1041269

Physical Properties

Molecular Weight 222.372 g/mol🔬 EPA CompTox
Density 1.036 g/cm^3🔬 EPA CTX
Boiling Point 285.5 °C🔬 EPA CTX
Melting Point 85.683 °C🔬 EPA CTX
Flash Point 119.385 °C📊 OPERA
Refractive Index 1.519 Dimensionless📊 OPERA
Molar Volume 220.265 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 4.377 Log10 unitless📊 OPERA
LogD (pH 5.5) 4.377 Log10 unitless📊 OPERA
LogD (pH 7.4) 4.377 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 9.23 Log10 unitless📊 OPERA
Water Solubility 0 mol/L📊 OPERA
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 1.05 mmHg🔬 EPA CTX
Surface Tension 35.101 dyn/cm📊 OPERA
Thermal Conductivity 119.93 mW/(m*K)📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 20.23 Ų💻 Computed
H-Bond Donors 1 count💻 Computed
H-Bond Acceptors 1 count💻 Computed
Rotatable Bonds 0 count💻 Computed
Aromatic Rings 0 count💻 Computed
Molar Refractivity 66.861 cm^3/mol📊 OPERA
Polarizability 26.506 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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