Cyclohexanepropanol, 2,2,3,6-tetramethyl-a-propyl- (CAS 95851-08-04) — Woody Base Note Fragrance Ingredient

Woody · Balsamic

Cyclohexanepropanol, 2,2,3,6-tetramethyl-a-propyl-

CAS 95851-08-04

Origin
synthetic
Note
Base
IFRA
Generally safe
Data as of: Apr 2026

What Is Cyclohexanepropanol, 2,2,3,6-tetramethyl-a-propyl-?

Cyclohexanepropanol, 2,2,3,6-tetramethyl-a-propyl- is a synthetic fragrance ingredient used in modern perfumery. It contributes woody, amber-like notes to fragrances. Consumers encounter it in fine fragrances, personal care products, and home scents. This ingredient matters because it provides long-lasting, diffusive woody-amber character that enhances fragrance performance and stability.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
Safe in regulated products
Check for individual sensitivity
CAS
95851-08-04
Formula
Mixture
MW
Variable
Odor Family
Woody · Balsamic
Layer 1 · Enthusiast

What Does Cyclohexanepropanol, 2,2,3,6-tetramethyl-a-propyl- Smell Like?

This synthetic molecule delivers a powerful woody-amber scent with subtle earthy undertones. The initial impression is dry and slightly resinous, like sun-baked driftwood. As it evolves, it reveals a warm, rounded character reminiscent of precious amber resins. The dry-down is persistent, leaving a clean, slightly musky trail that blends well with other base notes.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

Cyclohexanepropanol derivatives are synthetic molecules designed for perfumery. These compounds typically feature complex cyclohexane rings with various substituents that modify their olfactory properties. The 2,2,3,6-tetramethyl substitution pattern contributes to the molecule’s stability and woody-amber scent profile. Synthesis typically involves catalytic hydrogenation or Grignard reactions of appropriate precursors.

Physical & Chemical Properties

Perfumer Guide

Note Position
Base
Volatility
Low (hours-days)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance1-5%Up to 10%Provides woody-amber foundation
Personal Care0.5-3%Up to 5%Enhances longevity

Classic Accords

Tip: Use as a base note to anchor citrus or floral compositions.

Alternatives & Comparisons

1
Ambroxan CAS 6790-58-5

When a cleaner, more transparent amber effect is desired.

2
Norlimbanol CAS 70788-30-6

For a more diffusive, powerful woody-amber character.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No IFRA restrictions currently apply.

RIFM Assessment

Not currently assessed by RIFM.

Sustainability

As a synthetic ingredient, this compound is produced through controlled chemical processes. While it doesn’t rely on natural resources, its production requires petrochemical feedstocks. The environmental impact is moderate, with opportunities for green chemistry improvements in synthesis routes.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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