Ethyl alpha-ethyl-beta-methyl-beta-phenylglycidate (CAS 19464-94-9) — Sweet Top to middle Note Fragrance Ingredient

ByThe Good Scents
Sweet · Woody

Ethyl alpha-ethyl-beta-methyl-beta-phenylglycidate

CAS 19464-94-9

Origin
synthetic
Note
Top to middle
IFRA
Generally safe
Data as of: Apr 2026

What Is Ethyl alpha-ethyl-beta-methyl-beta-phenylglycidate?

Ethyl alpha-ethyl-beta-methyl-beta-phenylglycidate is a synthetic ester used in fragrances and flavorings. It imparts a fruity, strawberry-like aroma. Consumers encounter it in berry-flavored candies, desserts, and fruity perfumes. This ingredient matters because it creates realistic, long-lasting fruit notes that are difficult to achieve with natural extracts alone.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
✓ Approved for use in food and fragrances
⚠ Use in moderation due to potency
CAS
19464-94-9
Formula
Mixture
MW
Variable
Odor Family
Sweet · Woody
Layer 1 · Enthusiast

What Does Ethyl alpha-ethyl-beta-methyl-beta-phenylglycidate Smell Like?

A burst of ripe strawberries with jammy undertones, evolving into a candied fruitiness reminiscent of gummy bears. The dry-down reveals a subtle woody sweetness, like the lingering scent of a fruit-filled pastry. The aroma is vibrant yet smooth, with a slightly creamy texture that prevents it from becoming cloying.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Strawberry Fields Forever(Demeter, 2005)

Used to create the hyper-realistic strawberry note that defines this whimsical fragrance, blending synthetic precision with playful nostalgia.

Layer 2

2D Molecular Structure

Ethyl alpha-ethyl-beta-methyl-beta-phenylglycidate

SMILES: CCOC(=O)[C@]1(CC)O[C@@]1(C)C1=CC=CC=C1

Chemistry, Properties & Perfumer Guide

The Chemistry

Ethyl alpha-ethyl-beta-methyl-beta-phenylglycidate belongs to the ester class of organic compounds. It is synthesized through the reaction of ethyl glycidate with ethyl acetoacetate under acidic conditions. The resulting molecule features a phenyl group and multiple ester functionalities, contributing to its intense fruity character. Its synthetic nature allows for consistent quality and purity, unlike variable natural extracts.

Physical & Chemical Properties

Boiling PointNot readily available
DensityNot readily available

Perfumer Guide

Note Position
Top to middle
Volatility
Medium (1-3 hours)
Blending
Good with vanillin and other fruity notes
ApplicationTypical %RangeNotes
Fine Fragrance0.5-2%Up to 5%Adds fruity top notes
Flavors10-50 ppmUp to 100 ppmBerry flavor enhancer

Classic Accords

Tip: Use sparingly to avoid overpowering other notes; excellent for creating strawberry illusions.

Alternatives & Comparisons

1
Ethyl methylphenylglycidate CAS 77-83-8

A simpler variant with less ethyl substitution, offering a brighter strawberry character but less longevity.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No IFRA restrictions currently apply.

EU Allergen Declaration

Not listed as an EU allergen.

RIFM Assessment

RIFM has evaluated this compound as safe for use in fragrances at current levels.

Sustainability

As a synthetic material, this compound avoids agricultural impacts but relies on petrochemical feedstocks. Modern production methods aim to minimize waste and energy use.

Explore Ethyl alpha-ethyl-beta-methyl-beta-phenylglycidate

Browse essential oils and aroma compounds.

Browse on iHerb →

Affiliate disclosure: we may earn a small commission at no extra cost to you.

References

  1. PubChem Compound Summary for Ethyl alpha-ethyl-beta-methyl-beta-phenylglycidate PubChem CID: Not available

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

Report a data error

Ingredient Data Sheet

CAS 19464-94-9

Physical Properties

Molecular Weight234.29 g/mol🔬 PubChem
LogP (Octanol-Water)2.6🔬 PubChem
Boiling Point287 °C🔬 EPA CompTox
Vapor Pressure0.0002 mmHg @ 25°C📊 OPERA
Flash Point120 °C🔬 EPA CompTox
log Kp (skin permeability)-2.283💻 Calculated
SMILESCCC1(C(O1)(C)C2=CC=CC=C2)C(=O)OCC🔬 PubChem

Volatility & Performance

Fragrance NoteBase💻 Calculated
Volatility ClassVery slow💻 Calculated
Persistence Score6.9 / 5💻 Calculated

Odor & Flavor

Functional Groupsesteretheraromatic💻 RDKit
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

Physicochemical Properties

DTXSID: DTXSID40173106

Physical Properties

Molecular Weight 234.295 g/mol🔬 EPA CompTox
Density 1.083 g/cm^3📊 OPERA
Boiling Point 288.989 °C📊 OPERA
Melting Point 53.18 °C📊 OPERA
Flash Point 119.528 °C📊 OPERA
Refractive Index 1.508 Dimensionless📊 OPERA
Molar Volume 217.012 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 2.889 Log10 unitless📊 OPERA
LogD (pH 5.5) 2.889 Log10 unitless📊 OPERA
LogD (pH 7.4) 2.889 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 7.57 Log10 unitless📊 OPERA
Water Solubility 0.001 mol/L📊 OPERA
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0.001 mmHg📊 OPERA
Viscosity 1.696 cP📊 OPERA
Surface Tension 36.412 dyn/cm📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 38.83 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 3 count💻 Computed
Rotatable Bonds 4 count💻 Computed
Aromatic Rings 1 count💻 Computed
Molar Refractivity 64.702 cm^3/mol📊 OPERA
Polarizability 25.65 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

Similar Posts