Cyclohexyl methyl pentanone (CAS 4927-39-3) — Woody Middle Note Fragrance Ingredient

ByThe Good Scents
Woody · Green

Cyclohexyl methyl pentanone

CAS 4927-39-3

Origin
synthetic
Note
Middle
IFRA
Generally safe
Data as of: Apr 2026

What Is Cyclohexyl methyl pentanone?

Cyclohexyl methyl pentanone is a synthetic fragrance ingredient used in modern perfumery. It provides a fresh, slightly fruity note with woody undertones. This molecule is commonly found in laundry detergents, fabric softeners, and body care products where a clean, long-lasting scent is desired. Its stability and versatility make it popular in functional fragrances.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
✓ Safe in regulated products
⚠ Check for skin sensitivity in high concentrations
CAS
4927-39-3
Formula
Mixture
MW
Variable
Odor Family
Woody · Green
Layer 1 · Enthusiast

What Does Cyclohexyl methyl pentanone Smell Like?

Cyclohexyl methyl pentanone opens with a crisp, slightly green freshness reminiscent of crushed leaves, evolving into a subtle fruity sweetness akin to ripe pears. The dry-down reveals a smooth, woody character with faint musky undertones, providing excellent tenacity on fabrics. Its odor profile is linear but gains depth when blended with citrus or floral notes.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Clean Reserve Warm Cotton(Clean, 2015)

Used to enhance the fresh linen accord, providing long-lasting fabric-like freshness without excessive sweetness.

The Laundress Signature(The Laundress, 2012)

Contributes to the crisp, just-washed linen effect with excellent diffusion on fabrics.

Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

Cyclohexyl methyl pentanone is a synthetic ketone with a cyclohexyl group attached to a methyl pentanone backbone. It is produced through Friedel-Crafts acylation reactions or oxidation of corresponding alcohols. The molecule’s stability comes from its saturated cyclohexyl ring, making it resistant to oxidation in functional products.

Physical & Chemical Properties

Boiling PointNot publicly available
DensityNot publicly available

Perfumer Guide

Note Position
Middle
Volatility
Medium (2-6 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fabric Care1-3%Up to 5%Provides long-lasting freshness
Personal Care0.5-1.5%Up to 3%Used in body washes and deodorants

Classic Accords

Tip: Use with aldehydes C12 MNA to enhance diffusion in fabric care applications.

Alternatives & Comparisons

1
Cyclopentadecanone CAS 502-72-7

When a muskier dry-down is desired while maintaining similar fresh top notes.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not currently restricted by IFRA.

RIFM Assessment

No specific safety concerns identified by RIFM at typical usage levels.

Sustainability

As a synthetic ingredient, cyclohexyl methyl pentanone has consistent quality and doesn’t rely on natural resources. Modern production methods aim to minimize environmental impact through efficient catalysis and waste reduction.

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References

  1. PubChem Compound Summary for Cyclohexyl methyl pentanone PubChem
  2. IFRA Standards Library IFRA

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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