Dihydro-.gamma.-ionone (CAS 13720-12-2) — Floral Heart to base Note Fragrance Ingredient

Floral · Woody

Dihydro-.gamma.-ionone

CAS 13720-12-2

Origin
synthetic
Note
Heart to base
IFRA
Generally safe
Data as of: Apr 2026

What Is Dihydro-.gamma.-ionone?

Dihydro-γ-ionone is a synthetic fragrance ingredient prized for its soft, woody-orris character. You’ll encounter it in luxury perfumes, especially those with powdery or violet-like accords. This molecule matters because it bridges floral and woody notes, adding sophistication without overpowering. It’s a subtle workhorse behind many ‘your skin but better’ fragrances.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
No significant restrictions
Always patch test new formulations
CAS
13720-12-2
Formula
Mixture
MW
Variable
Odor Family
Floral · Woody
Layer 1 · Enthusiast

What Does Dihydro-.gamma.-ionone Smell Like?

Dihydro-γ-ionone unfolds like a silk handkerchief dusted with violet powder—initially a tender floralcy reminiscent of orris root and parma violets, then revealing a suede-like texture with whispers of raspberry jam. As it dries, the sweetness recedes into a polished woody base with the faintest hint of tea leaves. Unlike its more aggressive cousin α-ionone, this molecule lingers as a transparent veil rather than a bold statement, making it ideal for skin-scent effects.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Infusion d'Iris(Prada, 2007)

The powdery elegance of dihydro-γ-ionone amplifies the cosmetic quality of the orris, creating a fragrance that smells like high-end face powder in a carved wooden compact.

Insolence(Guerlain, 2006)

Here it softens the violet overdose, adding a plush quality that prevents the floral notes from becoming screechy or candied.

Layer 2

2D Molecular Structure

4-(2,2-Dimethyl-6-methylenecyclohexyl)butan-2-one

SMILES: CC(=O)CCC1C(=C)CCCC1(C)C

Chemistry, Properties & Perfumer Guide

The Chemistry

Dihydro-γ-ionone belongs to the ionone family of cyclic terpenoids, specifically a hydrogenated derivative of γ-ionone. Unlike α- and β-ionones which have conjugated double bonds, this saturated version offers greater stability and a more subdued olfactory profile. Industrial synthesis typically involves acid-catalyzed cyclization of pseudoionone followed by selective hydrogenation. The lack of chiral centers makes it easier to produce consistently compared to some natural isolates.

Physical & Chemical Properties

AppearanceColorless to pale yellow liquid
Boiling Point~250°C (estimated)
Density~0.93 g/cm³
Refractive Index~1.49

Perfumer Guide

Note Position
Heart to base
Volatility
Moderate (2-6 hours)
Blending
Excellent with florals and woods
ApplicationTypical %RangeNotes
Fine Fragrance1-5%Up to 8%For powdery-violet effects
Personal Care0.1-1%Up to 2%Soap-compatible floral modifier

Classic Accords

+ Orris + Sandalwood = Luxury powder + Rose + Ambroxan = Modern chypre + Heliotropin + Vanillin = Gourmand veil

Tip: Use with ionones to create depth without increasing perceived sweetness.

Alternatives & Comparisons

1
α-Ionone CAS 127-41-3

More intense violet character with higher impact but less subtlety. Better for bold floral statements.

2
Methyl Ionone CAS 1335-46-2

Woodier and more tenacious. Prefer for masculine or oriental compositions needing longevity.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No restrictions under current IFRA standards (Amendment 49).

RIFM Assessment

Considered safe for use in fragrance based on RIFM’s 2015 evaluation of structural analogs.

Sustainability

As a purely synthetic material, dihydro-γ-ionone avoids pressure on natural violet resources. Modern manufacturing routes have reduced solvent waste compared to earlier processes. The molecule’s potency means small quantities suffice, lowering overall environmental load versus weaker materials requiring higher doses.

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References

  1. Brenna et al. (2002). Ionones and damascones: Biotechnological production. Flavour and Fragrance Journal. DOI:10.1002/ffj.1096

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Physicochemical Properties

DTXSID: DTXSID1051694

Physical Properties

Molecular Weight 194.318 g/mol🔬 EPA CompTox
Density 0.889 g/cm^3📊 OPERA
Boiling Point 244.015 °C📊 OPERA
Melting Point 18.632 °C📊 OPERA
Flash Point 94.765 °C📊 OPERA
Refractive Index 1.462 Dimensionless📊 OPERA
Molar Volume 217.779 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 4.067 Log10 unitless📊 OPERA
LogD (pH 5.5) 4.067 Log10 unitless📊 OPERA
LogD (pH 7.4) 4.067 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 6.13 Log10 unitless📊 OPERA
Water Solubility 0.001 mol/L📊 OPERA
Henry's Law Constant 0 atm-m3/mole📊 OPERA

Transport Properties

Vapor Pressure 0.027 mmHg📊 OPERA
Viscosity 3.046 cP📊 OPERA
Surface Tension 30.22 dyn/cm📊 OPERA
Thermal Conductivity 129.175 mW/(m*K)📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 17.07 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 1 count💻 Computed
Rotatable Bonds 3 count💻 Computed
Aromatic Rings 0 count💻 Computed
Molar Refractivity 59.833 cm^3/mol📊 OPERA
Polarizability 23.72 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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