Ethylene glycol monobutyl ether (CAS 111-76-2) — Sweet N/A Note Fragrance Ingredient

Sweet · Citrus

Ethylene glycol monobutyl ether

CAS 111-76-2

Origin
synthetic
Note
N/A
IFRA
Professional use
Data as of: Apr 2026

What Is Ethylene glycol monobutyl ether?

Ethylene glycol monobutyl ether is a synthetic solvent used in industrial and household cleaning products. It helps dissolve oils and greases. While not commonly found in consumer fragrances, it may appear in some specialty formulations. Its use requires careful handling due to potential health effects.

Safety Profile

PROFESSIONAL USE
Generally safeUse with awarenessProfessional use
Potential skin irritant
Avoid inhalation
CAS
111-76-2
Formula
Mixture
MW
Variable
Odor Family
Sweet · Citrus
Layer 1 · Enthusiast

What Does Ethylene glycol monobutyl ether Smell Like?

Ethylene glycol monobutyl ether has a mild, somewhat sweet odor with a faintly chemical character. It lacks the complexity of traditional fragrance ingredients, presenting more as a functional solvent than a perfumery note. Its odor profile is linear, without significant evolution over time, and tends to remain in the background when used in formulations.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Layer 2

2D Molecular Structure

2-Butoxyethanol

SMILES: CCCCOCCO

Chemistry, Properties & Perfumer Guide

The Chemistry

Ethylene glycol monobutyl ether is a glycol ether with the formula C6H14O2. It is produced through the reaction of ethylene oxide with butanol. This class of compounds is valued for their solvent properties, particularly in industrial applications where they serve as coupling agents between water and organic materials.

Physical & Chemical Properties

Boiling Point171 °C
Density0.90 g/cm³
Flash Point60 °C

Perfumer Guide

Note Position
N/A
Volatility
N/A
Blending
N/A
ApplicationTypical %RangeNotes
IndustrialN/AN/APrimarily used as solvent

Classic Accords

Tip: Not recommended for perfumery use.

Alternatives & Comparisons

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not regulated by IFRA for fragrance use.

GHS Classification

H315 Skin irritation H319 Eye irritation H335 May cause respiratory irritation

RIFM Assessment

Not assessed by RIFM for fragrance use.

Sustainability

Industrial production raises environmental concerns due to petrochemical sourcing and potential toxicity. Proper disposal and handling are essential to minimize ecological impact.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Physicochemical Properties

    DTXSID: DTXSID1024097

    Physical Properties

    Molecular Weight 118.176 g/mol🔬 EPA CompTox
    Density 0.9 g/cm^3🔬 EPA CTX
    Boiling Point 170.47 °C🔬 EPA CTX
    Melting Point -70.21 °C🔬 EPA CTX
    Flash Point 62.091 °C🔬 EPA CTX
    Refractive Index 1.418 Dimensionless📊 OPERA
    Molar Volume 131.444 cm^3/mol📊 OPERA

    Partition & Solubility

    LogP (Octanol-Water) 0.859 Log10 unitless🔬 EPA CTX
    LogD (pH 5.5) 0.802 Log10 unitless📊 OPERA
    LogD (pH 7.4) 0.802 Log10 unitless📊 OPERA
    LogKoa (Octanol-Air) 4.9 Log10 unitless📊 OPERA
    Water Solubility 1.316 mol/L🔬 EPA CTX
    Henry's Law Constant 0 atm-m3/mole🔬 EPA CTX

    Transport Properties

    Vapor Pressure 5.643 mmHg🔬 EPA CTX
    Viscosity 3.997 cP📊 OPERA
    Surface Tension 28.976 dyn/cm📊 OPERA
    Thermal Conductivity 157.141 mW/(m*K)📊 OPERA

    Molecular Descriptors

    Topological Polar Surface Area 29.46 Ų💻 Computed
    H-Bond Donors 1 count💻 Computed
    H-Bond Acceptors 2 count💻 Computed
    Rotatable Bonds 5 count💻 Computed
    Aromatic Rings 0 count💻 Computed
    Molar Refractivity 33.126 cm^3/mol📊 OPERA
    Polarizability 13.132 Å^3📊 OPERA

    Data Sources:

    🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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