Garlic oil (CAS 8000-78-0) — Spicy Top/Heart Note Fragrance Ingredient

Spicy · Musky

Garlic oil

CAS 8000-78-0

Origin
natural
Note
Top/Heart
IFRA
Use with awareness
Data as of: Apr 2026

What Is Garlic oil?

Garlic oil is a potent essential oil derived from Allium sativum bulbs, commonly encountered in cooking and traditional medicine. Its strong, pungent aroma makes it unmistakable in kitchens worldwide. This oil matters in perfumery for adding depth to savory accords and creating unconventional, bold fragrance profiles that challenge traditional floral or citrus compositions.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
Strong odor – use sparingly
May cause skin irritation in high concentrations
CAS
8000-78-0
Formula
Mixture
MW
Variable
Odor Family
Spicy · Musky
Layer 1 · Enthusiast

What Does Garlic oil Smell Like?

Garlic oil erupts with an intensely pungent, sulfurous blast reminiscent of crushed cloves and kitchen preparations. The initial sharpness carries metallic undertones that evolve into a warm, savory heart with umami depth. Dry-down reveals lingering animalic notes and a peculiar sweetness akin to roasted onions. This challenging material requires expert handling but can add incredible realism to gourmand or avant-garde compositions.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Secretions Magnifiques(Etat Libre d’Orange, 2006)

Used minimally to amplify the controversial blood-like metallic notes, creating an unsettling realism in this provocative fragrance.

Blackpepper(Comme des Garçons, 2014)

Garlic oil adds a savory counterpoint to the spicy pepper accord, creating unexpected culinary depth.

Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

Garlic oil contains numerous sulfur compounds including allicin (diallyl thiosulfinate), diallyl disulfide, and ajoene. These organosulfur molecules form when garlic cells are damaged, releasing alliinase enzymes that convert alliin to volatile compounds. The oil’s characteristic odor comes primarily from these reactive sulfur species, which are unstable and continue transforming after extraction.

Physical & Chemical Properties

AppearancePale yellow liquid
Odor StrengthExtremely high

Perfumer Guide

Note Position
Top/Heart
Volatility
Moderate (2-4 hours)
Blending
Challenging
ApplicationTypical %RangeNotes
Fine Fragrance0.01-0.1%Up to 0.5%Used as an accent note
Functional Fragrance0.001-0.01%Trace amountsMasking agent

Classic Accords

+ Cumin + Black Pepper = Savory Spice + Leather + Birch Tar = Animalic Brutality

Tip: Dilute to 1% or lower before incorporating to prevent overwhelming the composition.

Alternatives & Comparisons

1
Onion Oil CAS 8002-72-0

Provides similar sulfury notes but with less intensity and more sweetness, suitable when a softer effect is desired.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No specific IFRA restrictions, but general guidelines recommend low usage due to potency.

EU Allergen Declaration

Contains diallyl disulfide and other potential sensitizers – may require allergen declaration.

GHS Classification

H315 Skin irritation H319 Eye irritation H335 May cause respiratory irritation

RIFM Assessment

RIFM recommends maximum dermal exposure of 0.02% based on skin sensitization potential.

Sustainability

Garlic cultivation has low environmental impact, but oil extraction yields are poor (approximately 0.1-0.2% from fresh bulbs). Most commercial production comes from China using steam distillation. Synthetic sulfur compounds can replicate some effects with greater consistency and lower agricultural footprint.

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References

  1. Block E. (2010). Garlic and Other Alliums: The Lore and the Science. Royal Society of Chemistry. ISBN 9780854041909
  2. Lawson LD. (1996). The composition and chemistry of garlic cloves and processed garlic. ACS Symposium Series. DOI 10.1021/bk-1996-0637.ch001

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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