Heptyl D-glucoside (CAS 1627851-18-6) — Sweet Non-olfactive Note Fragrance Ingredient

ByThe Good Scents
Sweet · Citrus

Heptyl D-glucoside

CAS 1627851-18-6

Origin
synthetic
Note
Non-olfactive
IFRA
Generally safe
Data as of: Apr 2026

What Is Heptyl D-glucoside?

Heptyl D-glucoside is a synthetic sugar-based surfactant commonly found in gentle cleansers and shampoos. It helps create mild foaming action while being biodegradable. This ingredient matters because it offers a plant-derived alternative to harsher detergents, making it popular in ‘clean beauty’ formulations for sensitive skin.

Safety Profile

GENERALLY SAFE
Generally safeUse with awarenessProfessional use
✓ Biodegradable and eco-friendly
✓ Gentle on sensitive skin
CAS
1627851-18-6
Formula
Mixture
MW
Variable
Odor Family
Sweet · Citrus
Layer 1 · Enthusiast

What Does Heptyl D-glucoside Smell Like?

Heptyl D-glucoside is nearly odorless with only a faint, clean sweetness reminiscent of diluted sugar water. Its olfactory profile is intentionally neutral to avoid interfering with fragrance systems in personal care products. The molecule lacks volatile top notes or evolving characteristics, serving purely as a functional surfactant rather than a perfumery material.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

Heptyl D-glucoside belongs to the alkyl polyglycoside (APG) class of non-ionic surfactants, synthesized through the Fischer glycosylation reaction between glucose and heptanol. The D-glucose moiety provides water solubility while the heptyl chain confers mild surfactant properties. As a single isomer (D-configuration), it offers consistent performance compared to mixed glycoside preparations. Modern synthesis routes emphasize green chemistry principles with high atom economy.

Physical & Chemical Properties

AppearanceColorless to pale yellow liquid
SolubilityWater-soluble

Perfumer Guide

Note Position
Non-olfactive
Volatility
Non-volatile
Blending
N/A
ApplicationTypical %RangeNotes
Cleansers5-15%1-30%Primary surfactant
Shampoos3-10%1-20%Mild foaming agent

Classic Accords

Tip: Use as a base surfactant system component where mildness and biodegradability are priorities.

Alternatives & Comparisons

1
Decyl Glucoside CAS 141464-42-8

Similar sugar surfactant with slightly stronger cleansing power due to longer alkyl chain.

2
Coco-Glucoside CAS 110615-47-9

Mixed chain length glucosides derived from coconut alcohol, offering cost-effective mild cleansing.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not restricted by IFRA – classified as non-perfuming ingredient

RIFM Assessment

Recognized as safe for use in cosmetic formulations by RIFM.

Sustainability

Produced from renewable glucose and plant-derived alcohols, Heptyl D-glucoside meets OECD biodegradability standards. Its synthesis typically avoids petrochemical feedstocks, and the molecule breaks down readily in wastewater systems without forming toxic metabolites. The environmental profile makes it preferred over traditional sulfated surfactants in eco-certified products.

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References

  1. OECD (2019). Surfactant Biodegradability Testing Guidelines. OECD Series 301
  2. Hill, K. (2002). Alkyl Polyglycosides: Technology and Applications. Wiley-VCH. ISBN 3-527-30264-9

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Perfumer’s Notes

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