Indane Musk (Phantolide) (CAS 15323-35-0) — Musky Base Note Fragrance Ingredient
Indane Musk (Phantolide)
CAS 15323-35-0
What Is Indane Musk (Phantolide)?
Indane Musk (Phantolide) is a synthetic musk used in perfumes and household products for its long-lasting, warm scent. You’ll encounter it in laundry detergents, fabric softeners, and prestige fragrances. This ingredient matters because it provides an affordable alternative to natural musks, offering consistent performance and stability in various formulations.
Safety Profile
USE WITH AWARENESSWhat Does Indane Musk (Phantolide) Smell Like?
Indane Musk delivers a clean, powdery musk with subtle animalic undertones. It starts with a slightly metallic sharpness that quickly softens into a velvety warmth reminiscent of sunbaked skin. Over hours, it becomes a skin-like scent with a comforting, slightly sweet dry-down. The effect is like a well-worn cashmere sweater—soft, intimate, and subtly luxurious.
Scent Profile
In Famous Fragrances
Fragrance associations may not reflect actual formulations.
Used here for its clean, laundry-like quality that makes musk approachable for everyday wear.
Provides the creamy skin-scent foundation that made this celebrity perfume iconic.
2D Molecular Structure
SMILES: CC1C(C)(C)C2=C(C=C(C(C)=O)C(C)=C2)C1(C)C
Chemistry, Properties & Perfumer Guide
The Chemistry
Phantolide belongs to the polycyclic musk class, synthesized from indane derivatives. These compounds mimic natural muscone but with greater stability. The synthesis typically involves Friedel-Crafts alkylation to create the characteristic fused ring structure that gives these musks their persistence.
Physical & Chemical Properties
| Appearance | White crystalline powder |
|---|---|
| Boiling Point | Not readily available |
| Melting Point | Not readily available |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Laundry Products | 0.1-0.5% | Up to 1% | Provides lasting freshness |
| Fine Fragrance | 1-3% | Up to 5% | Foundation for musk accords |
Classic Accords
Tip: Use with ionones to soften the metallic edge in top notes.
Alternatives & Comparisons
When a cleaner, more diffusive musk is needed without animalic nuances.
For a more powdery, vintage character in traditional compositions.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. IFRA, REACH, EU Cosmetics Regulation standards update periodically. Consult current IFRA Standards Library before formulating. Not legal or regulatory advice.
IFRA Status
Not currently restricted by IFRA.
RIFM Assessment
RIFM considers this material safe at current usage levels.
Sustainability
As a synthetic, Phantolide avoids the ethical concerns of animal-derived musks but raises questions about environmental persistence. Modern wastewater treatment plants effectively remove most polycyclic musks, reducing ecological impact compared to early formulations.
Explore Indane Musk (Phantolide)
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References
Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Mar 2026.
Report a data errorIngredient Data Sheet
CAS 15323-35-0Physical Properties
| Molecular Weight | 244.37 g/mol🔬 PubChem |
| LogP (Octanol-Water) | 4.8🔬 PubChem |
| Boiling Point | 316 °C🔬 EPA CompTox |
| Vapor Pressure | 0 mmHg @ 25°C📊 OPERA |
| Flash Point | 140.5 °C🔬 EPA CompTox |
| log Kp (skin permeability) | -0.783💻 Calculated |
| SMILES | CC1C(C2=C(C1(C)C)C=C(C(=C2)C)C(=O)C)(C)C🔬 PubChem |
Volatility & Performance
| Fragrance Note | Base💻 Calculated |
| Volatility Class | Very slow💻 Calculated |
| Persistence Score | 12.4 / 5💻 Calculated |
Odor & Flavor
| Primary Descriptors | musky• leffingwell |
| Functional Groups | ketonearomatic💻 RDKit |
Sensory Thresholds
| Odor Detection Threshold | 0.0067 ppm📖 van Gemert |
Regulatory Status
| IFRA Listed | Yes — see IFRA Standards for category limits⚖️ IFRA 51 |
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.
Physicochemical Properties
DTXSID: DTXSID9051743
Physical Properties
| Molecular Weight | 244.378 g/mol🔬 EPA CompTox |
| Density | 0.001 g/cm^3🔬 EPA CTX |
| Boiling Point | 316 °C🔬 EPA CTX |
| Melting Point | 58.1 °C🔬 EPA CTX |
| Flash Point | 135.077 °C📊 OPERA |
| Refractive Index | 1.494 Dimensionless📊 OPERA |
| Molar Volume | 263.15 cm^3/mol📊 OPERA |
Partition & Solubility
| LogP (Octanol-Water) | 5.59 Log10 unitless🔬 EPA CTX |
| LogD (pH 5.5) | 5.284 Log10 unitless📊 OPERA |
| LogD (pH 7.4) | 5.284 Log10 unitless📊 OPERA |
| LogKoa (Octanol-Air) | 8.41 Log10 unitless📊 OPERA |
| Water Solubility | 0 mol/L🔬 EPA CTX |
| Henry's Law Constant | 0 atm-m3/mole📊 OPERA |
Transport Properties
| Vapor Pressure | 0 mmHg🔬 EPA CTX |
| Surface Tension | 31.162 dyn/cm📊 OPERA |
| Thermal Conductivity | 109.841 mW/(m*K)📊 OPERA |
Molecular Descriptors
| Topological Polar Surface Area | 17.07 Ų💻 Computed |
| H-Bond Donors | 0 count💻 Computed |
| H-Bond Acceptors | 1 count💻 Computed |
| Rotatable Bonds | 1 count💻 Computed |
| Aromatic Rings | 1 count💻 Computed |
| Molar Refractivity | 76.631 cm^3/mol📊 OPERA |
| Polarizability | 30.379 Å^3📊 OPERA |
Data Sources:
🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.
