Isopropyl cinnamate (CAS 7780-06-05) — Balsamic Middle Note Fragrance Ingredient
Isopropyl cinnamate
CAS 7780-06-05
What Is Isopropyl cinnamate?
Isopropyl cinnamate is a synthetic fragrance ingredient commonly found in perfumes and personal care products. It contributes a warm, balsamic character reminiscent of cinnamon and vanilla. This ester is valued for its ability to add depth and longevity to fragrance compositions, often appearing in oriental and woody accords.
Safety Profile
USE WITH AWARENESSWhat Does Isopropyl cinnamate Smell Like?
Isopropyl cinnamate unfolds with an initial burst of warm cinnamon spice that quickly mellows into a rich, balsamic heart. The dry-down reveals a velvety vanilla-like sweetness with subtle woody undertones. Its character evolves like spiced honey dripping over aged oak, maintaining excellent tenacity while avoiding cloying heaviness. The ester’s balanced profile makes it particularly useful for bridging citrus top notes with deeper base accords.
In Famous Fragrances
Fragrance associations may not reflect actual formulations.
Chemistry, Properties & Perfumer Guide
The Chemistry
Isopropyl cinnamate is an ester formed by the condensation of cinnamic acid with isopropanol. As a synthetic material, it’s typically produced via acid-catalyzed esterification. The molecule features a conjugated double bond system that contributes to its warm olfactory character and good stability in formulations.
Physical & Chemical Properties
| Boiling Point | ~250 °C (estimated) |
|---|---|
| Density | ~1.0 g/cm³ (estimated) |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Fine Fragrance | 1-3% | Up to 5% | Oriental bases modifier |
| Soap | 0.5-1% | Up to 2% | Adds warmth to spicy accords |
Classic Accords
Tip: Use to soften harsh spice notes while maintaining warmth in oriental compositions.
Alternatives & Comparisons
Offers similar spicy character with brighter top notes and less balsamic depth.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
No IFRA restrictions currently apply (as of Amendment 49).
GHS Classification
RIFM Assessment
RIFM evaluation complete – safe for current use levels in fragrance.
Sustainability
As a synthetic material, isopropyl cinnamate avoids agricultural supply chain issues. Production typically uses petrochemical feedstocks, though bio-based routes from cinnamic acid are being explored.
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References
- Bauer et al. (2001). Common Fragrance and Flavor Materials. Wiley-VCH.
Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.
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