N-[2-(2,6-Dimethylphenyl)amino]-2-oxoethyl]-N,N-diethylbenzenemethana minium benzoate (CAS 3734-33-6) — Citrus Heart Note Fragrance Ingredient

Citrus · Floral

N-[2-(2,6-Dimethylphenyl)amino]-2-oxoethyl]-N,N-diethylbenzenemethana minium benzoate

CAS 3734-33-6

Origin
synthetic
Note
Heart
IFRA
Professional use
Data as of: Apr 2026

What Is N-[2-(2,6-Dimethylphenyl)amino]-2-oxoethyl]-N,N-diethylbenzenemethana minium benzoate?

This synthetic compound is a specialized ingredient primarily used in industrial fragrance applications. Consumers may encounter trace amounts in certain air fresheners or cleaning products. While not commonly found in fine fragrances, it serves as a building block for more complex scent molecules in professional perfumery.

Safety Profile

PROFESSIONAL USE
Generally safeUse with awarenessProfessional use
Restricted industrial handling
Not for consumer formulation
CAS
3734-33-6
Formula
Mixture
MW
Variable
Odor Family
Citrus · Floral
Layer 1 · Enthusiast

What Does N-[2-(2,6-Dimethylphenyl)amino]-2-oxoethyl]-N,N-diethylbenzenemethana minium benzoate Smell Like?

Layer 2

2D Molecular Structure

Denatonium benzoate

SMILES: [O-]C(=O)C1=CC=CC=C1.CC[N+](CC)(CC(=O)NC1=C(C)C=CC=C1C)CC1=CC=CC=C1

Chemistry, Properties & Perfumer Guide

The Chemistry

This quaternary ammonium compound features a complex structure with benzene rings and diethylamino groups. As a synthetic molecule, it’s produced through multi-step organic synthesis involving alkylation and benzoylation reactions. The compound’s cationic nature makes it more suitable for functional applications than olfactive purposes in perfumery.

Physical & Chemical Properties

Perfumer Guide

Note Position
Volatility
Medium
Blending
Good
ApplicationTypical %RangeNotes
IndustrialTrace0.1-1%Intermediate chemical processing

Classic Accords

Tip: Handle only in controlled laboratory environments with proper PPE.

Alternatives & Comparisons

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not evaluated by IFRA – industrial chemical intermediate

RIFM Assessment

No RIFM evaluation available

Sustainability

This synthetic compound is produced through petrochemical routes with standard industrial safety protocols. Environmental impact is managed through controlled manufacturing processes and waste stream treatment.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Ingredient Data Sheet

    CAS 3734-33-6

    Physical Properties

    Molecular Weight446.6 g/mol🔬 PubChem
    Boiling Point369 °C🔬 EPA CompTox
    Vapor Pressure0 mmHg @ 25°C📊 OPERA
    Flash Point100 °C🔬 EPA CompTox
    SMILESCC[N+](CC)(CC1=CC=CC=C1)CC(=O)NC2=C(C=CC=C2C)C.C1=CC=C(C=C1)C(=O)[O-]🔬 PubChem

    Volatility & Performance

    Fragrance NoteBase💻 Calculated

    Odor & Flavor

    Functional Groupsaromatic💻 RDKit
    Data Sources & Attribution
    Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

    Physicochemical Properties

    DTXSID: DTXSID8034376

    Physical Properties

    Molecular Weight 446.591 g/mol🔬 EPA CompTox
    Density 0.54 g/cm^3🔬 EPA CTX
    Boiling Point 369 °C📊 OPERA
    Melting Point 166.667 °C🔬 EPA CTX
    Flash Point 100 °C🔬 EPA CTX

    Partition & Solubility

    LogP (Octanol-Water) 2.131 Log10 unitless🔬 EPA CTX
    LogD (pH 5.5) 0.17 Log10 unitless📊 OPERA
    LogD (pH 7.4) 0.72 Log10 unitless📊 OPERA
    LogKoa (Octanol-Air) 10.51 Log10 unitless📊 OPERA
    Water Solubility 0.095 mol/L🔬 EPA CTX
    Henry's Law Constant 0 atm-m3/mole📊 OPERA

    Transport Properties

    Vapor Pressure 0 mmHg📊 OPERA

    Molecular Descriptors

    Topological Polar Surface Area 69.23 Ų💻 Computed
    H-Bond Donors 1 count💻 Computed
    H-Bond Acceptors 3 count💻 Computed
    Rotatable Bonds 8 count💻 Computed
    Aromatic Rings 3 count💻 Computed
    Molar Refractivity 131.67 cm^3/mol💻 Computed

    Data Sources:

    🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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