Nonane, 2,2,4,4,6,8,8-heptamethyl- (CAS 4390-04-09) — Woody Base Note Fragrance Ingredient
Nonane, 2,2,4,4,6,8,8-heptamethyl-
CAS 4390-04-09
What Is Nonane, 2,2,4,4,6,8,8-heptamethyl-?
Nonane, 2,2,4,4,6,8,8-heptamethyl- is a synthetic fragrance ingredient used in modern perfumery. It’s found in niche and avant-garde fragrances where unique dry woody-amber effects are desired. This molecule contributes to the ‘skin scent’ trend in perfumery, creating subtle yet persistent olfactory effects that interact with body chemistry.
Safety Profile
USE WITH AWARENESSWhat Does Nonane, 2,2,4,4,6,8,8-heptamethyl- Smell Like?
This synthetic molecule presents a complex olfactory profile – initially crisp with a metallic, almost gasoline-like sharpness that quickly evolves into a warm, dry woody-amber character. The dry-down reveals its true magic: an intimate skin-scent effect that blends seamlessly with body chemistry, creating a subtle yet persistent aura of warmth. Perfumers value its ability to add diffusion and tenacity without overwhelming other notes, functioning as an invisible amplifier in modern compositions.
In Famous Fragrances
Fragrance associations may not reflect actual formulations.
Showcases this ingredient as a solo act, demonstrating its transformative dry-down from sharp synthetic opening to warm skin-hugging base.
Uses it as an invisible backbone to amplify the saffron-amber accord while adding subtle woody diffusion.
Chemistry, Properties & Perfumer Guide
The Chemistry
2,2,4,4,6,8,8-Heptamethylnonane is a branched alkane synthesized through petroleum refining processes. The highly branched structure contributes to its unique physical properties and olfactory characteristics. As a saturated hydrocarbon, it’s chemically inert and stable, making it useful in fragrance applications where longevity is desired. The molecular symmetry and lack of functional groups result in low polarity and high hydrophobicity.
Physical & Chemical Properties
| Appearance | Colorless liquid |
|---|---|
| Boiling Point | ~220-240°C (estimated) |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Fine Fragrance | 0.5-2% | Up to 5% | Used for diffusion and dry-down effects |
| Functional Fragrance | 0.1-0.5% | Up to 1% | Adds subtle persistence |
Classic Accords
Tip: Use in trace amounts with woody-ambers to enhance diffusion without altering the main accord.
Alternatives & Comparisons
Offers similar woody diffusion but with more pronounced cedar-like character and better understood safety profile.
Provides amber persistence without the initial sharpness, though lacks the skin-scent effect.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
Not currently restricted by IFRA. Due to limited safety data, conservative usage is recommended.
RIFM Assessment
No complete RIFM assessment available as of 2023. Considered a novel fragrance material.
Sustainability
As a petroleum-derived synthetic, its environmental impact depends on production methods. Some manufacturers are exploring bio-based routes to similar branched alkanes. The material’s longevity in fragrance reduces the need for reapplication, potentially offsetting some environmental impact through reduced consumption.
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References
- Branched Alkanes in Modern Perfumery Industry publication
Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.
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