Periploca sepium oil (CAS 1155405-59-6) — Woody Base Note Fragrance Ingredient

Woody · Balsamic

Periploca sepium oil

CAS 1155405-59-6

Origin
natural
Note
Base
IFRA
Use with awareness
Data as of: Apr 2026

What Is Periploca sepium oil?

Periploca sepium oil is a rare botanical extract derived from the bark of the Chinese silk vine. It’s occasionally found in niche perfumery and traditional Chinese medicine. This ingredient matters for its unique aromatic profile that bridges woody and balsamic characteristics, offering perfumers an unconventional material with cultural significance in East Asian fragrance traditions.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
Traditional use in herbal medicine
Limited safety data available
CAS
1155405-59-6
Formula
Mixture
MW
Variable
Odor Family
Woody · Balsamic
Layer 1 · Enthusiast

What Does Periploca sepium oil Smell Like?

Periploca sepium oil unfolds with an initial medicinal sharpness reminiscent of aged leather and dried herbs. The heart reveals a complex interplay of bitter cocoa and damp tree bark, with subtle resinous undertones that recall frankincense tears. As it dries down, the oil develops a warm, slightly animalic base note akin to sun-baked stones in a forest clearing, leaving a lingering impression of ancient woodlands.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Memoirs of a Trespasser(Imaginary Authors, 2015)

Used for its woody-balsamic duality that enhances the vanilla and myrrh accord, creating a sense of forbidden exploration in abandoned places.

Provides an earthy counterpoint to the amber accord, adding depth to the fragrance’s dry, mineralic character.

Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

Periploca sepium oil contains a complex mixture of cardiac glycosides, phenolic compounds, and terpenoids. The primary aromatic constituents include periplocin and periplocymarin, which contribute to its distinctive medicinal-woody character. Extraction typically involves steam distillation of the dried bark, yielding a viscous oil with variable composition depending on harvest conditions.

Physical & Chemical Properties

AppearanceViscous brownish liquid
SolubilitySparingly soluble in water

Perfumer Guide

Note Position
Base
Volatility
Low (8+ hours)
Blending
Moderate
ApplicationTypical %RangeNotes
Fine Fragrance0.1-0.5%Up to 1%Used as an accent note
Incense1-3%Up to 5%Adds depth to resinous blends

Classic Accords

+ Labdanum + Patchouli = Dark ambery base + Vetiver + Oakmoss = Forest floor accord

Tip: Use sparingly in oriental compositions to add mysterious depth without overwhelming the blend.

Alternatives & Comparisons

1
Quassia amara extract CAS 68990-67-0

Offers similar bitter-woody notes when a more readily available material is needed, though lacks the balsamic complexity.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No specific IFRA restrictions. General guidelines for botanical extracts apply.

RIFM Assessment

No RIFM assessment available due to limited commercial use.

Sustainability

Wild harvesting of Periploca sepium raises ecological concerns due to slow growth rates. Sustainable cultivation programs are being developed in China, but most material still comes from wild sources. Synthetic alternatives are not currently available due to the oil’s complex composition.

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References

  1. Chinese Pharmacopoeia Commission. (2020). Periplocae Cortex monograph.

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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