Propanol, 1(or 2)-(2-methoxymethylethoxy)-, acetate (CAS 88917-22-0) — Citrus Heart Note Fragrance Ingredient

Citrus · Floral

Propanol, 1(or 2)-(2-methoxymethylethoxy)-, acetate

CAS 88917-22-0

Origin
synthetic
Note
Heart
IFRA
Use with awareness
Data as of: Apr 2026

What Is Propanol, 1(or 2)-(2-methoxymethylethoxy)-, acetate?

This synthetic ingredient is a specialized chemical used in fragrance formulations. It’s not commonly encountered in consumer products but may appear in some modern perfumes. As a synthetic molecule, it offers perfumers precise control over scent profiles and performance characteristics.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
No major restrictions in current IFRA guidelines
Limited safety data available
CAS
88917-22-0
Formula
Mixture
MW
Variable
Odor Family
Citrus · Floral
Layer 1 · Enthusiast

What Does Propanol, 1(or 2)-(2-methoxymethylethoxy)-, acetate Smell Like?

Layer 2

2D Molecular Structure

Dipropyleneglycol methyl ether acetate

SMILES: CC(COC)OCC(C)OC(=O)C

Chemistry, Properties & Perfumer Guide

The Chemistry

This compound is a synthetic ether-alcohol acetate derivative. The molecular structure combines ether and ester functional groups, which influences its volatility and scent characteristics. Production typically involves controlled etherification and subsequent acetylation reactions under laboratory conditions. The exact stereochemistry depends on the synthesis route.

Physical & Chemical Properties

Perfumer Guide

Note Position
Volatility
Medium
Blending
Good
ApplicationTypical %RangeNotes
Fine FragranceTrace-1%Up to 3%Specialty modifier

Classic Accords

Tip:

Alternatives & Comparisons

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not currently restricted by IFRA standards.

RIFM Assessment

No RIFM assessment currently available.

Sustainability

As a synthetic material, production requires petrochemical feedstocks. The environmental impact depends on manufacturing processes and energy inputs. No known natural sources exist.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Ingredient Data Sheet

    CAS 88917-22-0

    Physical Properties

    Molecular Weight190.24 g/mol🔬 PubChem
    LogP (Octanol-Water)0.7🔬 PubChem
    Boiling Point209 °C🔬 EPA CompTox
    Vapor Pressure0.12 mmHg @ 25°C📊 OPERA
    Flash Point86 °C🔬 EPA CompTox
    Involatility Index0.0094💻 Calculated
    log Kp (skin permeability)-3.363💻 Calculated
    SMILESCC(COC)OCC(C)OC(=O)C🔬 PubChem

    Volatility & Performance

    Fragrance NoteHeart💻 Calculated
    Volatility ClassVery slow💻 Calculated
    Persistence Score1.2 / 5💻 Calculated

    Odor & Flavor

    Functional Groupsesterether💻 RDKit
    Data Sources & Attribution
    Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

    Physicochemical Properties

    DTXSID: DTXSID4029062

    Physical Properties

    Molecular Weight 190.24 g/mol🔬 PubChem
    Density 0.98 g/cm^3🔬 PubChem
    Boiling Point 209 °C🔬 PubChem
    Flash Point 86 °C🔬 PubChem

    Partition & Solubility

    LogP (Octanol-Water) 0.7 Log10 unitless🔬 PubChem

    Transport Properties

    Vapor Pressure 0.12 mmHg🔬 PubChem

    Molecular Descriptors

    Topological Polar Surface Area 44.76 Ų💻 Computed
    H-Bond Donors 0 count💻 Computed
    H-Bond Acceptors 4 count💻 Computed
    Rotatable Bonds 6 count💻 Computed
    Molar Refractivity 48.52 cm^3/mol💻 Computed

    Data Sources:

    🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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