Pyridine, 4-ethenyl-, reaction products with 3a,4,7,7a-tetrahydrodimethyl-4,7-methano-1H-indene (CAS 125352-06-9) — Woody Variable Note Fragrance Ingredient

Woody · Balsamic

Pyridine, 4-ethenyl-, reaction products with 3a,4,7,7a-tetrahydrodimethyl-4,7-methano-1H-indene

CAS 125352-06-9

Origin
synthetic
Note
Variable
IFRA
Professional use
Data as of: Apr 2026

What Is Pyridine, 4-ethenyl-, reaction products with 3a,4,7,7a-tetrahydrodimethyl-4,7-methano-1H-indene?

This synthetic ingredient is a specialized fragrance compound used in modern perfumery. It’s typically found in niche and avant-garde fragrances where unique molecular structures create unconventional scent profiles. The material offers perfumers a tool for creating contemporary, abstract accords that push beyond traditional floral or woody compositions.

Safety Profile

PROFESSIONAL USE
Generally safeUse with awarenessProfessional use
Limited safety data available
Requires professional handling
CAS
125352-06-9
Formula
Mixture
MW
Variable
Odor Family
Woody · Balsamic
Layer 1 · Enthusiast

What Does Pyridine, 4-ethenyl-, reaction products with 3a,4,7,7a-tetrahydrodimethyl-4,7-methano-1H-indene Smell Like?

This synthetic molecule presents a sharp, metallic edge with complex aromatic nuances. The initial impression suggests hot iron filings with an underlying medicinal quality, evolving into a dry, woody-amber character. As it dries down, subtle pyridine-like facets emerge – think of the electric tang of ozone after a thunderstorm blended with the faintest whisper of aged leather. The dry-down reveals surprising tenacity, leaving an almost mineralic trail reminiscent of volcanic rocks warmed by the sun.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

This compound belongs to the pyridine derivative class, created through specialized reactions between vinylpyridine and dimethylmethanoindene precursors. The synthesis involves controlled cycloaddition reactions that create complex bicyclic structures. The resulting molecule exhibits unique electronic properties due to the nitrogen-containing aromatic system conjugated with the indene-derived framework. While exact stereochemistry isn’t publicly documented, the reaction likely produces multiple stereoisomers contributing to its multifaceted olfactory profile.

Physical & Chemical Properties

AppearanceNot documented
Molecular WeightNot documented

Perfumer Guide

Note Position
Variable
Volatility
Medium-Long
Blending
Specialized
ApplicationTypical %RangeNotes
Experimental Fragrance0.1-0.5%Up to 1%Used for avant-garde effects
Functional ProductsNot recommendedN/ANot typically used

Classic Accords

Tip: Use sparingly as a modifier in modern woody-amber bases to add cutting-edge metallic facets.

Alternatives & Comparisons

1
Pyridine CAS 110-86-1

Simpler pyridine structure for sharper medicinal effects without the complex woody-amber dry-down.

2
Ambroxan CAS 6790-58-5

Provides amber-woody character without metallic nuances for more conventional applications.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No specific IFRA restrictions documented. Use professional judgment due to limited safety data.

RIFM Assessment

No RIFM assessment publicly available for this specific compound.

Sustainability

As a synthetic material, this compound’s environmental impact depends on manufacturing processes. The specialized synthesis suggests moderate energy requirements. Being used in trace amounts minimizes ecological burden. No known natural alternatives exist for its unique olfactory profile.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Ingredient Data Sheet

    CAS 125352-06-9
    Data Sources & Attribution
    Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

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